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伊拉克基尔库克有不良产科史的妇女的巨细胞病毒血清流行率。

Cytomegalovirus seroprevalence in women with bad obstetric history in Kirkuk, Iraq.

机构信息

Department of Microbiology, Tikrit University College of Medicine, Tikrit, Iraq; Kirkuk Health Authority, Iraq.

Department of Medicine, Tikrit University College of Medicine, Tikrit, Iraq; Department of Microbiology, Tikrit University College of Medicine, Tikrit, Iraq; Asthma, Allergy Centre, Tikrit Teaching Hospital, Tikrit, Iraq.

出版信息

J Infect Public Health. 2014 Jul-Aug;7(4):277-88. doi: 10.1016/j.jiph.2013.08.006. Epub 2014 Mar 12.

Abstract

The human cytomegalovirus (CMV) is a major cause of congenital infections. A case-control descriptive study was conducted in Kirkuk, Iraq to determine the seroprevalence of CMV in women with bad obstetric history (BOH) compared to women with a normal previous pregnancy. The CMV IgG and IgM seroprevalence was higher in women with BOH. The CMV IgG seroprevalence was significantly influenced by pregnancy, age, residence and level of education. In addition, the current CMV infection was significantly associated with pregnancy, age, residence and education. Large families (crowding index >3) exhibited higher seroprevalence for CMV IgM (8.3%) and IgG (98.3%), but odd ratio (OR) showed no significant association between family size and seropositivity. The CMV IgG seropositivity was higher in working women (100%) compared to housewives (95.4%). However, the CMV IgM (current infection) was 6.8% in housewives and was not detected in any working women (0%). The OR exhibited no significant association between occupation and both IgM and IgG levels.

摘要

人类巨细胞病毒(CMV)是先天性感染的主要原因。在伊拉克基尔库克进行了一项病例对照描述性研究,以确定有不良产科史(BOH)的妇女与正常既往妊娠的妇女相比,CMV 的血清流行率。CMV IgG 和 IgM 的血清流行率在 BOH 妇女中更高。CMV IgG 血清流行率受妊娠、年龄、居住地和教育程度的显著影响。此外,目前的 CMV 感染与妊娠、年龄、居住地和教育程度显著相关。大家庭(拥挤指数>3)的 CMV IgM(8.3%)和 IgG(98.3%)的血清阳性率更高,但优势比(OR)显示家庭规模与血清阳性率之间没有显著关联。与家庭主妇(95.4%)相比,职业女性(100%)的 CMV IgG 血清阳性率更高。然而,家庭主妇的 CMV IgM(当前感染)为 6.8%,没有在任何职业女性中检测到(0%)。OR 显示职业与 IgM 和 IgG 水平之间没有显著关联。

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