Department of Aquatic Life Medicine, Pukyong National University, Busan 608-737, Republic of Korea.
Department of Aquatic Life Medicine, Pukyong National University, Busan 608-737, Republic of Korea.
Ecotoxicol Environ Saf. 2014 Jun;104:96-102. doi: 10.1016/j.ecoenv.2014.02.010. Epub 2014 Mar 15.
Juvenile Pagrus major (mean length 15.8±1.6cm, and mean weight 90.4±4.7g) were exposed for 4 weeks with waterborne selenium concentration (0, 50, 100, 200, and 400µg/L). The profile of Se accumulation among tissue in P. major is dependent on the exposure periods and Se concentration. After 4 weeks, the highest accumulation of Se was observed in the kidney, and the order of Se accumulation in tissues was kidney≈liver>spleen>intestine>gill>muscle. Se decreased the growth rate, and there was an inverse proportion between growth and Se concentration. The major hematological findings were significant decrease in the RBC count, Ht value, and Hb concentration exposed to ≥100µg/L Se concentrations. Se exposure (≥100µg/L) led to significant increase in the glucose, GOT, and GPT levels, whereas the levels of calcium, magnesium, cholesterol, and total protein did not increase. The results suggest that waterborne Se exposure can induce significant Se accumulation in tissues, inhibition of growth, and hematological alterations.
幼年真鲷（平均体长 15.8±1.6cm，平均体重 90.4±4.7g）暴露于水中硒浓度（0、50、100、200 和 400µg/L）4 周。真鲷组织中的硒积累模式取决于暴露时间和硒浓度。4 周后，肾脏中硒的积累最高，组织中硒的积累顺序为肾脏≈肝脏>脾脏>肠>鳃>肌肉。硒降低了生长率，生长率与硒浓度呈反比。主要的血液学发现是暴露于≥100µg/L 硒浓度时 RBC 计数、Ht 值和 Hb 浓度显著下降。硒暴露（≥100µg/L）导致葡萄糖、GOT 和 GPT 水平显著升高，而钙、镁、胆固醇和总蛋白水平没有升高。结果表明，水基硒暴露会导致组织中硒的显著积累、生长抑制和血液学改变。
