Kaur Charanpreet, Ghosh Ajit, Pareek Ashwani, Sopory Sudhir K, Singla-Pareek Sneh L
*International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.
†School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Biochem Soc Trans. 2014 Apr;42(2):485-90. doi: 10.1042/BST20130242.
The glyoxalase pathway is required for detoxification of cytotoxic metabolite MG (methylglyoxal) that would otherwise increase to lethal concentrations under adverse environmental conditions. Since its discovery 100 years ago, several roles have been assigned to glyoxalases, but, in plants, their involvement in stress response and tolerance is the most widely accepted role. The plant glyoxalases have emerged as multigene family and this expansion is considered to be important from the perspective of maintaining a robust defence machinery in these sessile species. Glyoxalases are known to be differentially regulated under stress conditions and their overexpression in plants confers tolerance to multiple abiotic stresses. In the present article, we review the importance of glyoxalases in plants, discussing possible roles with emphasis on involvement of the glyoxalase pathway in plant stress tolerance.
乙二醛酶途径对于细胞毒性代谢物MG（甲基乙二醛）的解毒是必需的，否则在不利的环境条件下，MG会增加到致死浓度。自100年前被发现以来，乙二醛酶已被赋予了多种功能，但在植物中，它们参与应激反应和耐受性是最被广泛认可的功能。植物乙二醛酶已成为一个多基因家族，从在这些固着生物中维持强大的防御机制的角度来看，这种扩展被认为是重要的。已知乙二醛酶在应激条件下受到差异调节，它们在植物中的过表达赋予了对多种非生物胁迫的耐受性。在本文中，我们综述了乙二醛酶在植物中的重要性，讨论了其可能的作用，重点是乙二醛酶途径在植物胁迫耐受性中的参与。
