单通道记录中的速率-幅度相关性。离子通道门控动力学中的隐藏结构？
Rate-amplitude correlation from single-channel records. A hidden structure in ion channel gating kinetics?
作者信息
Millhauser G L, Salpeter E E, Oswald R E
机构信息
Department of Pharmacology, New York State College of Veterinary Medicine Cornell University, Ithaca 14853.
出版信息
Biophys J. 1988 Dec;54(6):1165-8. doi: 10.1016/S0006-3495(88)83051-0.
Abstract
Lifetime probability density functions from single-channel recording are usually assumed to follow a multiexponential form. The amplitudes and rate constants for each exponential component are presumed to be independent. We have explored this assumption and have found a correlation between the amplitudes and the rate constants in certain cases. We examine this correlation and the possibility that other functional forms may also properly describe these distribution functions.
摘要
单通道记录的终身概率密度函数通常被假定遵循多指数形式。每个指数成分的幅度和速率常数被认为是独立的。我们研究了这一假设，并发现在某些情况下幅度和速率常数之间存在相关性。我们研究了这种相关性以及其他函数形式也可能恰当地描述这些分布函数的可能性。
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