Palaniappan Ramanathan Ramanathan, Chandrasekaran Baskaran
Department of Pulmonary Medicine, Peelamedu Samanaidu Govindarajulu Hospitals, Peelamedu, Coimbatore, Tamil Nadu, India.
Lung India. 2014 Jan;31(1):35-8. doi: 10.4103/0970-2113.125892.
Six-min walk test (6MWT), a simple functional capacity evaluation tool used globally to determine the prognosis and effectiveness of any therapeutic/medical intervention. However, variability in reference equations derived from western population (due to racial and ethnicity variations) hinders from adequate use of 6MWT clinically. Further, there are no valid Indian studies that predict reference values for 6-min walk distance (6MWD) in healthy Indian normal.
We aimed for framing individualized reference equations for 6MWT in healthy Indian population.
Anthropometric variables (age, weight, height, and body mass index (BMI)) and 6-min walk in a 30 m corridor were evaluated in 125 subjects (67 females) in a cross-sectional trial.
6MWD significantly correlated with age (r = -0.29), height (r = 0.393), weight (r = 0.08), and BMI (r = -0.17). The gender specific reference equations for healthy Indian individuals were: (1) Males: 561.022 - (2.507 × age [years]) + (1.505 × weight [kg]) - (0.055 × height [cm]). R (2) = 0.288. (2) Indian females: 30.325 - (0.809 × age [years]) - (2.074 × weight [kg]) + (4.235 × height [cm]). R (2) = 0.272. Though the equations possess a small coefficient of determination and larger standard error estimate, the former applicability to Indian population is justified.
These reference equations are probably most appropriate for evaluating the walked capacity of Indian patients with chronic diseases.
六分钟步行试验（6MWT）是一种全球通用的简单功能能力评估工具，用于确定任何治疗/医疗干预的预后和效果。然而，源自西方人群的参考方程存在变异性（由于种族和民族差异），这阻碍了6MWT在临床上的充分应用。此外，尚无有效的印度研究来预测健康印度正常人的六分钟步行距离（6MWD）参考值。
我们旨在为健康印度人群制定6MWT的个体化参考方程。
在一项横断面试验中，对125名受试者（67名女性）进行了人体测量变量（年龄、体重、身高和体重指数（BMI））以及在30米走廊内的六分钟步行评估。
6MWD与年龄（r = -0.29）、身高（r = 0.393）、体重（r = 0.08）和BMI（r = -0.17）显著相关。健康印度个体的性别特异性参考方程为：（1）男性：561.022 - （2.507×年龄[岁]） + （1.505×体重[千克]） - （0.055×身高[厘米]）。R（2） = 0.288。（2）印度女性：30.325 - （0.809×年龄[岁]） - （2.074×体重[千克]） + （4.235×身高[厘米]）。R（2） = 0.272。尽管这些方程的决定系数较小且标准误差估计值较大，但前者对印度人群的适用性是合理的。
这些参考方程可能最适合评估印度慢性病患者的步行能力。
