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智能手机应用程序辅助戒酒:一项随机临床试验。

A smartphone application to support recovery from alcoholism: a randomized clinical trial.

机构信息

Center for Health Enhancement Systems Studies, College of Engineering, University of Wisconsin-Madison.

North Shore Medical Center, Salem, Massachusetts.

出版信息

JAMA Psychiatry. 2014 May;71(5):566-72. doi: 10.1001/jamapsychiatry.2013.4642.

Abstract

IMPORTANCE

Patients leaving residential treatment for alcohol use disorders are not typically offered evidence-based continuing care, although research suggests that continuing care is associated with better outcomes. A smartphone-based application could provide effective continuing care.

OBJECTIVE

To determine whether patients leaving residential treatment for alcohol use disorders with a smartphone application to support recovery have fewer risky drinking days than control patients.

DESIGN, SETTING, AND PARTICIPANTS: An unmasked randomized clinical trial involving 3 residential programs operated by 1 nonprofit treatment organization in the Midwestern United States and 2 residential programs operated by 1 nonprofit organization in the Northeastern United States. In total, 349 patients who met the criteria for DSM-IV alcohol dependence when they entered residential treatment were randomized to treatment as usual (n = 179) or treatment as usual plus a smartphone (n = 170) with the Addiction-Comprehensive Health Enhancement Support System (A-CHESS), an application designed to improve continuing care for alcohol use disorders.

INTERVENTIONS

Treatment as usual varied across programs; none offered patients coordinated continuing care after discharge. A-CHESS provides monitoring, information, communication, and support services to patients, including ways for patients and counselors to stay in contact. The intervention and follow-up period lasted 8 and 4 months, respectively.

MAIN OUTCOMES AND MEASURES

Risky drinking days--the number of days during which a patient's drinking in a 2-hour period exceeded 4 standard drinks for men and 3 standard drinks for women, with standard drink defined as one that contains roughly 14 g of pure alcohol (12 oz of regular beer, 5 oz of wine, or 1.5 oz of distilled spirits). Patients were asked to report their risky drinking days in the previous 30 days on surveys taken 4, 8, and 12 months after discharge from residential treatment.

RESULTS

For the 8 months of the intervention and 4 months of follow-up, patients in the A-CHESS group reported significantly fewer risky drinking days than did patients in the control group, with a mean of 1.39 vs 2.75 days (mean difference, 1.37; 95% CI, 0.46-2.27; P = .003).

CONCLUSIONS AND RELEVANCE

The findings suggest that a multifeatured smartphone application may have significant benefit to patients in continuing care for alcohol use disorders.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT01003119.

摘要

重要性

离开酒精使用障碍住院治疗的患者通常无法获得基于证据的延续性护理,尽管研究表明延续性护理与更好的治疗结果相关。智能手机应用程序可能提供有效的延续性护理。

目的

确定患有酒精使用障碍的患者在离开住院治疗后,使用智能手机应用程序来支持康复治疗,与对照组相比,有多少天的风险饮酒日。

设计、设置和参与者:这是一项未设盲的随机临床试验,涉及美国中西部的 1 家非营利性治疗组织运营的 3 家住院治疗机构,以及美国东北部的 1 家非营利性组织运营的 2 家住院治疗机构。共有 349 名符合 DSM-IV 酒精依赖标准的患者进入住院治疗,他们被随机分配到常规治疗组(n=179)或常规治疗加智能手机组(n=170),智能手机使用了 Addiction-Comprehensive Health Enhancement Support System(A-CHESS),这是一款旨在改善酒精使用障碍的延续性护理的应用程序。

干预措施

常规治疗在各个项目中有所不同;出院后没有任何项目为患者提供协调一致的延续性护理。A-CHESS 为患者提供监测、信息、沟通和支持服务,包括患者和顾问保持联系的方式。干预和随访期分别持续 8 个月和 4 个月。

主要结果和测量

风险饮酒日-患者在 2 小时内饮酒量超过男性 4 标准杯和女性 3 标准杯的天数,标准杯定义为含有约 14 克纯酒精的饮料(12 盎司普通啤酒、5 盎司葡萄酒或 1.5 盎司蒸馏酒)。患者在出院后 30 天内通过调查报告他们的风险饮酒日,调查时间为出院后 4、8 和 12 个月。

结果

在干预的 8 个月和随访的 4 个月期间,A-CHESS 组的患者报告的风险饮酒日明显少于对照组,平均为 1.39 天和 2.75 天(平均差异为 1.37;95%CI,0.46-2.27;P=.003)。

结论和相关性

研究结果表明,多特征智能手机应用程序可能对酒精使用障碍患者的延续性护理有显著益处。

试验注册

clinicaltrials.gov 标识符:NCT01003119。

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