单纯疱疹病毒1型生物学与生命周期。
HSV-1 biology and life cycle.
作者信息
Everett Roger D
机构信息
MRC-University of Glasgow Centre for Virus Research, 8 Church Street, Glasgow, G11 5JR, Scotland UK,
出版信息
Methods Mol Biol. 2014;1144:1-17. doi: 10.1007/978-1-4939-0428-0_1.
Herpes simplex virus type 1 (HSV-1) is a common and important human pathogen that has been studied in a wide variety of contexts for several decades. This book presents chapters on protocols on many strands of HSV-1 research that are currently in use in leading laboratories. This chapter gives a brief overview of HSV-1 biology and life cycle, covering basic aspects of the virus and its replication in cultured cells, the diseases caused by the virus, viral latency, antiviral defenses, and the mechanisms that the virus uses to counteract these defenses.
单纯疱疹病毒1型（HSV - 1）是一种常见且重要的人类病原体，几十年来已在各种各样的背景下得到研究。本书呈现了目前在顶尖实验室中使用的关于HSV - 1多方面研究方案的章节。本章简要概述了HSV - 1的生物学特性和生命周期，涵盖了病毒的基本方面及其在培养细胞中的复制、病毒引起的疾病、病毒潜伏、抗病毒防御以及病毒用于对抗这些防御的机制。
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