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宫内人工授精中的精液制备技术:不明原因不孕症病例中非温度控制离心与温度控制离心的比较。

Semen preparation techniques in intrauterine insemination: A comparison of non-temperature and temperature controlled centrifugation in cases of unexplained infertility.

作者信息

Selvaraj Priya, Selvaraj Kamala, Kalaichelvi S, Mahalakshmi R

机构信息

Department of Research, Fertility Research Centre, GG Hospital, Chennai, Tamil Nadu, India.

出版信息

J Hum Reprod Sci. 2013 Oct;6(4):241-4. doi: 10.4103/0974-1208.126289.

DOI:10.4103/0974-1208.126289
PMID:24672162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3963306/
Abstract

AIM

The aim of the following study is to compare pregnancy rates between the use of non-temperature and temperature controlled centrifugation on semen preparation technique in intrauterine insemination.

MATERIALS AND METHODS

The retrospective study was conducted on 671 patients of idiopathic infertility who underwent homologous artificial insemination at Fertility Research Center from the period of January 2007 to September 2012. The couples were randomized into two groups namely, Group A-patients (n = 303) being treated with sperm prepared by using non-temperature controlled centrifuge and Group B-Patients (n = 368) being treated with sperm prepared by temperature (37°C) controlled centrifuge.

RESULTS AND CONCLUSION

The clinical pregnancy rate Group A was 13.86% and Group B was 12.77%. The clinical pregnancy fetal loss rate between the two groups was 38% and 42% respectively. The delivery rate per transfer was 62% and 58% respectively. No statistically significant difference was found between these two groups.

摘要

目的

以下研究的目的是比较在宫腔内人工授精中,使用非温度控制离心和温度控制离心的精液制备技术的妊娠率。

材料与方法

对2007年1月至2012年9月期间在生育研究中心接受同种人工授精的671例特发性不孕症患者进行回顾性研究。这些夫妇被随机分为两组,即A组(n = 303),患者接受使用非温度控制离心机制备的精子治疗;B组(n = 368),患者接受使用温度(37°C)控制离心机制备的精子治疗。

结果与结论

A组临床妊娠率为13.86%,B组为12.77%。两组临床妊娠胎儿丢失率分别为38%和42%。每次移植的分娩率分别为62%和58%。两组之间未发现统计学上的显著差异。

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Influence of the number of motile spermatozoa inseminated and of their morphology on the success of intrauterine insemination.授精时活动精子数量及其形态对宫腔内人工授精成功率的影响。
Hum Reprod. 2004 Sep;19(9):2060-5. doi: 10.1093/humrep/deh390. Epub 2004 Jul 8.
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Urology. 2002 Sep;60(3):497-501. doi: 10.1016/s0090-4295(02)01773-9.
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