Yiallouros Panayiotis K, Economou Mary, Kolokotroni Ourania, Savva Savvas C, Gavatha Marina, Ioannou Phivos, Karpathios Themistoclis, Middleton Nicos
Cyprus International Institute for Environmental & Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus; Department of Pediatrics, Hospital "Archbishop Makarios III", Nicosia, Cyprus.
Pediatr Pulmonol. 2015 Apr;50(4):317-26. doi: 10.1002/ppul.23045. Epub 2014 Mar 28.
To compare objectively assessed physical activity levels, between asthmatic children and non-asthmatic controls.
From a random community sample of 794 children aged 8-9 years, in a case-control design, 104 children with ever doctor's diagnosis of asthma and 99 non-asthmatic controls were recruited and had assessment of physical activity with biaxial accelerometers for 7 days.
Children with active (also reporting at least one episode of wheezing in the last 12 months) and inactive (no wheezing in past 12 months) asthma appeared to have similar physical activity and sedentary activity levels compared to non-asthmatic children. However, girls with active asthma had significantly lower moderate-to-vigorous physical activity (MVPA) levels than their peers with adjusted geometric mean ratio of 0.59 (95% CI: 0.369, 0.929, P-value = 0.024). No difference in physical and sedentary activity levels was observed between asthmatic and non-asthmatic boys. The difference between genders in the comparison of MVPA levels in asthmatics and controls was statistically significant (P-value of likelihood ratio test [LRT] for effect modification by gender = 0.034).
Unlike boys, girls with active asthma appear to be less active than their healthy peers, and this gender difference might explain the inconsistent evidence from previous reports on physical activity levels in asthmatic children. Further studies are needed to confirm the gender interaction in the childhood asthma-physical activity relation and the implications on current guidelines for physical exercise prescriptions in asthmatic children.
比较经客观评估的哮喘儿童与非哮喘对照儿童的身体活动水平。
在一项病例对照设计中，从794名8 - 9岁儿童的随机社区样本中，招募了104名曾被医生诊断为哮喘的儿童和99名非哮喘对照儿童，并使用双轴加速度计对他们的身体活动进行了7天的评估。
与非哮喘儿童相比，患有活动性哮喘（过去12个月内也报告至少有一次喘息发作）和非活动性哮喘（过去12个月内无喘息发作）的儿童似乎具有相似的身体活动和久坐活动水平。然而，患有活动性哮喘的女孩的中度至剧烈身体活动（MVPA）水平显著低于同龄人，调整后的几何平均比为0.59（95%可信区间：0.369, 0.929，P值 = 0.024）。在哮喘男孩和非哮喘男孩之间未观察到身体活动和久坐活动水平的差异。哮喘患者与对照者在MVPA水平比较中的性别差异具有统计学意义（性别效应修正的似然比检验[LRT]的P值 = 0.034）。
与男孩不同，患有活动性哮喘的女孩似乎比健康同龄人活动量少，这种性别差异可能解释了先前关于哮喘儿童身体活动水平的报告中不一致的证据。需要进一步研究来证实儿童哮喘与身体活动关系中的性别相互作用以及对当前哮喘儿童体育锻炼处方指南的影响。
