Ring J, Przybilla B, Eberlein B
Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, FRG.
Int Arch Allergy Appl Immunol. 1989;88(1-2):136-8. doi: 10.1159/000234767.
Irradiation of human peripheral leukocytes with ultraviolet A (UVA) induced a significant and dose-dependent reduction of anti-IgE or Ca-ionophore-stimulated histamine release without consistent influence upon C5a-induced release reactions. This effect was equally demonstrable in atopics and controls. In the presence of the radical scavenger superoxide dismutase, the UVA-induced inhibition of anti-IgE-induced histamine release was abolished. Under the conditions used, UVB exposure did not result in relevant changes of in vitro histamine release.
用紫外线A（UVA）照射人外周血白细胞，可显著且剂量依赖性地降低抗IgE或钙离子载体刺激的组胺释放，而对C5a诱导的释放反应无一致影响。这种效应在特应性个体和对照组中同样明显。在存在自由基清除剂超氧化物歧化酶的情况下，UVA诱导的抗IgE诱导的组胺释放抑制作用被消除。在所使用的条件下，紫外线B（UVB）照射未导致体外组胺释放的相关变化。
