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水果和蔬菜摄入量与全因死亡率、癌症死亡率和心血管疾病死亡率:基于英格兰健康调查数据的分析

Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data.

作者信息

Oyebode Oyinlola, Gordon-Dseagu Vanessa, Walker Alice, Mindell Jennifer S

机构信息

Health and Social Surveys Research Group, Department of Epidemiology & Public Health, UCL (University College London), London, UK.

出版信息

J Epidemiol Community Health. 2014 Sep;68(9):856-62. doi: 10.1136/jech-2013-203500. Epub 2014 Mar 31.

Abstract

BACKGROUND

Governments worldwide recommend daily consumption of fruit and vegetables. We examine whether this benefits health in the general population of England.

METHODS

Cox regression was used to estimate HRs and 95% CI for an association between fruit and vegetable consumption and all-cause, cancer and cardiovascular mortality, adjusting for age, sex, social class, education, BMI, alcohol consumption and physical activity, in 65 226 participants aged 35+ years in the 2001-2008 Health Surveys for England, annual surveys of nationally representative random samples of the non-institutionalised population of England linked to mortality data (median follow-up: 7.7 years).

RESULTS

Fruit and vegetable consumption was associated with decreased all-cause mortality (adjusted HR for 7+ portions 0.67 (95% CI 0.58 to 0.78), reference category <1 portion). This association was more pronounced when excluding deaths within a year of baseline (0.58 (0.46 to 0.71)). Fruit and vegetable consumption was associated with reduced cancer (0.75 (0.59-0.96)) and cardiovascular mortality (0.69 (0.53 to 0.88)). Vegetables may have a stronger association with mortality than fruit (HR for 2 to 3 portions 0.81 (0.73 to 0.89) and 0.90 (0.82 to 0.98), respectively). Consumption of vegetables (0.85 (0.81 to 0.89) per portion) or salad (0.87 (0.82 to 0.92) per portion) were most protective, while frozen/canned fruit consumption was apparently associated with increased mortality (1.17 (1.07 to 1.28) per portion).

CONCLUSIONS

A robust inverse association exists between fruit and vegetable consumption and mortality, with benefits seen in up to 7+ portions daily. Further investigations into the effects of different types of fruit and vegetables are warranted.

摘要

背景

世界各国政府都建议每日食用水果和蔬菜。我们研究了这是否对英国普通人群的健康有益。

方法

在2001 - 2008年英国健康调查中,对65226名35岁及以上的参与者进行了研究。该调查是对英国非机构化人口具有全国代表性的随机样本进行的年度调查,并与死亡率数据相关联(中位随访时间:7.7年)。使用Cox回归来估计水果和蔬菜摄入量与全因死亡率、癌症死亡率和心血管死亡率之间关联的风险比(HR)和95%置信区间(CI),并对年龄、性别、社会阶层、教育程度、体重指数、饮酒量和身体活动进行了调整。

结果

水果和蔬菜摄入量与全因死亡率降低相关(7份及以上的调整后HR为0.67(95%CI为0.58至0.78),参考类别为<1份)。当排除基线后一年内的死亡病例时,这种关联更为明显(0.58(0.46至0.71))。水果和蔬菜摄入量与癌症死亡率降低(0.75(0.59 - 0.96))和心血管死亡率降低(0.69(0.53至0.88))相关。蔬菜与死亡率的关联可能比水果更强(2至3份的HR分别为0.81(0.73至0.89)和0.90(0.82至0.98))。蔬菜(每份0.85(0.81至0.89))或沙拉(每份0.87(0.82至0.92))的摄入量最具保护作用,而冷冻/罐装水果的摄入量显然与死亡率增加相关(每份1.17(1.07至1.28))。

结论

水果和蔬菜摄入量与死亡率之间存在强烈的负相关,每天摄入7份及以上有益。有必要进一步研究不同类型水果和蔬菜的影响。

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