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亚的斯亚贝巴警戒医院皮肤利什曼病的近期趋势。

Recent trends of cutaneous leishmaniasis in Alert Hospital, Addis Ababa.

作者信息

Bekele Shiferaw, Bekele Yonas, Mulatu Fikerte, Lemma Tsehaynesh, Tilahun Hiwot, Gadisa Endalamaw, Negussie Shimelis, Yamuah Lawrence, Wassie Liya, Abebe Markos, Hiletework Mengistae, Hunegnaw Mesfin, Leekassa Rute, Bizuneh Elisabeth

出版信息

Ethiop Med J. 2014 Jan;Suppl 1:37-41.

PMID:24696987
Abstract

BACKGROUND

Cutaneous leishmaniasis is endemic to many parts of the world and has re-emerged in a number of endemic countries in recent years. Environmental changes, immune status of the host and treatment failure are the three most important risk factors associated with the re-emerging and spread of Leishmaniasis. Cutaneous leishmaniasis (CL) ranges from localized, self-healing type to the disfiguring mucocutaneous and diffuse cutaneous type.

OBJECTIVE

To access the trend of CL patient flow in ALERT Hospital, Addis Ababa, Ethiopia.

METHODS

Patients' clinical and laboratory records were collected retrospectively for 1651 leishmaniasis suspected individuals from ALERT Hospital, from January 1, 2007 to December 30, 2010.

RESULTS

From the suspected individuals, 234 cases were positive for Leishmania species with Giemsa stain and/or histopathology and confirmed for CL, of whom 30 (12.8%) were diagnosed in 2007, 29 (12.4%) in 2008, 75 (32.1%) in 2009, and 100 (42.7%) were in 2010.

CONCLUSIONS AND RECOMMENDATIONS

The overall proportion of cases with leishmaniasis among the suspected cases was 234/1651 (14.2%). The distribution of CL reports was higher for patients coming from Addis Ababa surrounding areas and Oromia region, 96/234 (41.03%) and 71/234 (30.34%), respectively. In general, the trend of leishmaniasis in and around Addis Ababa seems to be increasing, which calls for further detailed epidemiological studies, including vector and reservoir host studies, to help in the prevention and control of the disease.

摘要

背景

皮肤利什曼病在世界许多地区流行,近年来在一些流行国家再度出现。环境变化、宿主免疫状态和治疗失败是与利什曼病再度出现和传播相关的三个最重要风险因素。皮肤利什曼病(CL)范围从局限性、自愈型到毁容性黏膜皮肤型和弥漫性皮肤型。

目的

了解埃塞俄比亚亚的斯亚贝巴ALERT医院CL患者流量趋势。

方法

回顾性收集2007年1月1日至2010年12月30日期间ALERT医院1651例疑似利什曼病患者的临床和实验室记录。

结果

在疑似患者中,234例经吉姆萨染色和/或组织病理学检查利什曼原虫属阳性,确诊为CL,其中2007年诊断出30例(12.8%),2008年29例(12.4%),2009年75例(32.1%),2010年100例(42.7%)。

结论与建议

疑似病例中利什曼病病例的总体比例为234/1651(14.2%)。来自亚的斯亚贝巴周边地区和奥罗米亚地区的CL报告分布较高,分别为96/234(41.03%)和71/234(30.34%)。总体而言,亚的斯亚贝巴及其周边地区的利什曼病趋势似乎在增加,这需要进一步进行详细的流行病学研究,包括媒介和储存宿主研究,以帮助预防和控制该疾病。

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