替诺福韦诱发范科尼综合征：低钾性麻痹的罕见病因。
Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis.
作者信息
Venkatesan E P, Pranesh M B, Gnanashanmugam G, Balasubramaniam J
机构信息
Department of Neurology, PSG Institute of Medical Science and Research, Coimbatore, India.
Department of Nephrology, Kidney Care Centre, Thirunelveli, Tamil Nadu, India.
出版信息
Indian J Nephrol. 2014 Mar;24(2):108-9. doi: 10.4103/0971-4065.127898.
Abstract
We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.
摘要
我们报告了一名55岁女性，她因急性四肢瘫来到急诊科。7年前她被诊断为获得性免疫缺陷综合征，在过去10个月中接受基于替诺福韦的抗逆转录病毒治疗。由于该患者还存在低磷血症、糖尿和蛋白尿，怀疑患有范科尼综合征（FS）。在接下来的12小时内她显著好转，恢复了正常肌力，并且在接下来的几天里肾功能也有所改善。替诺福韦诱发的FS表现为低钾性麻痹是一种非常罕见的并发症，这是印度报道的首例病例。
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