地中海饮食与糖尿病：预防与治疗。
Mediterranean diet and diabetes: prevention and treatment.
机构信息
Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Street, Athens 17671, Greece.
出版信息
Nutrients. 2014 Apr 4;6(4):1406-23. doi: 10.3390/nu6041406.
Abstract
The aim of the present review is to examine current scientific knowledge on the association between the Mediterranean diet and diabetes mellitus (mostly type 2 diabetes). A definition of the Mediterranean diet and the tools widely used to evaluate adherence to this traditional diet (Mediterranean diet indices) are briefly presented. The review focuses on epidemiological data linking adherence to the Mediterranean diet with the risk of diabetes development, as well as evidence from interventional studies assessing the effect of the Mediterranean diet on diabetes control and the management of diabetes-related complications. The above mentioned data are explored on the basis of evaluating the Mediterranean diet as a whole dietary pattern, rather than focusing on the effect of its individual components. Possible protective mechanisms of the Mediterranean diet against diabetes are also briefly discussed.
摘要
本次综述的目的在于探讨当前关于地中海饮食与糖尿病（主要是 2 型糖尿病）之间关联的科学知识。本文简要介绍了地中海饮食的定义以及广泛用于评估这种传统饮食方式依从性的工具（地中海饮食指数）。本综述重点关注将地中海饮食与糖尿病发病风险联系起来的流行病学数据，以及评估地中海饮食对糖尿病控制和糖尿病相关并发症管理影响的干预性研究证据。上述数据是基于评估地中海饮食作为一种整体饮食模式的效果来探讨的，而不是关注其个别成分的效果。本文还简要讨论了地中海饮食预防糖尿病的可能保护机制。
相似文献
1
Mediterranean diet and diabetes: prevention and treatment.地中海饮食与糖尿病：预防与治疗。
Nutrients. 2014 Apr 4;6(4):1406-23. doi: 10.3390/nu6041406.
2
The role of diet in prevention and management of type 2 diabetes: implications for public health.饮食在 2 型糖尿病的预防和管理中的作用：对公共卫生的影响。
Crit Rev Food Sci Nutr. 2012;52(5):382-9. doi: 10.1080/10408398.2010.500258.
3
Yearly attained adherence to Mediterranean diet and incidence of diabetes in a large randomized trial.在一项大型随机试验中，每年对地中海饮食的依从情况与糖尿病的发病率。
Cardiovasc Diabetol. 2023 Sep 29;22(1):262. doi: 10.1186/s12933-023-01994-2.
4
Adherence to a Mediterranean diet and risk of diabetes: a systematic review and meta-analysis.坚持地中海饮食与糖尿病风险：一项系统评价与荟萃分析。
Public Health Nutr. 2015 May;18(7):1292-9. doi: 10.1017/S1368980014001542. Epub 2014 Aug 22.
5
Mediterranean diet and metabolic diseases.地中海饮食与代谢性疾病。
Curr Opin Lipidol. 2008 Feb;19(1):63-8. doi: 10.1097/MOL.0b013e3282f2fa4d.
6
Impact of a Mediterranean Dietary Pattern and Its Components on Cardiovascular Risk Factors, Glucose Control, and Body Weight in People with Type 2 Diabetes: A Real-Life Study.地中海饮食模式及其成分对 2 型糖尿病患者心血管危险因素、血糖控制和体重的影响：一项真实世界研究。
Nutrients. 2018 Aug 10;10(8):1067. doi: 10.3390/nu10081067.
7
Diabetes mellitus and abnormal glucose tolerance development after gestational diabetes: A three-year, prospective, randomized, clinical-based, Mediterranean lifestyle interventional study with parallel groups.妊娠期糖尿病后糖尿病和异常糖耐量的发展：一项为期三年的前瞻性、随机、基于临床的平行组地中海式生活方式干预研究。
Clin Nutr. 2015 Aug;34(4):579-85. doi: 10.1016/j.clnu.2014.09.005. Epub 2014 Sep 16.
8
The effect of Mediterranean diet on the development of type 2 diabetes mellitus: a meta-analysis of 10 prospective studies and 136,846 participants.地中海饮食对2型糖尿病发生发展的影响：一项对10项前瞻性研究和136,846名参与者的荟萃分析。
Metabolism. 2014 Jul;63(7):903-11. doi: 10.1016/j.metabol.2014.04.010. Epub 2014 Apr 24.
9
Mediterranean diet and multiple health outcomes: an umbrella review of meta-analyses of observational studies and randomised trials.地中海饮食与多种健康结局：观察性研究和随机试验荟萃分析的伞式评价。
Eur J Clin Nutr. 2018 Jan;72(1):30-43. doi: 10.1038/ejcn.2017.58. Epub 2017 May 10.
10
Prevention and control of type 2 diabetes by Mediterranean diet: a systematic review.地中海饮食预防和控制 2 型糖尿病：系统评价。
Diabetes Res Clin Pract. 2010 Aug;89(2):97-102. doi: 10.1016/j.diabres.2010.04.019. Epub 2010 May 23.
引用本文的文献
1
The Impact of Different Dietary Patterns on Mortality and Prognosis After Non-Metastatic Prostate Cancer Diagnosis: A Systematic Review.不同饮食模式对非转移性前列腺癌诊断后死亡率和预后的影响：一项系统综述
Healthcare (Basel). 2025 Sep 2;13(17):2201. doi: 10.3390/healthcare13172201.
2
The Impact of a Multidimensional Physical Activity Intervention on Glycemic Control in Type 1 Diabetes: A Preliminary Study.多维体育活动干预对1型糖尿病血糖控制的影响：一项初步研究。
J Funct Morphol Kinesiol. 2025 May 7;10(2):163. doi: 10.3390/jfmk10020163.
3
Effect of olive oil consumption on diabetes risk: a dose-response meta-analysis.食用橄榄油对糖尿病风险的影响：一项剂量反应荟萃分析。
J Health Popul Nutr. 2025 Apr 24;44(1):135. doi: 10.1186/s41043-025-00866-7.
4
Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study.认知障碍与地中海饮食及死亡率的相关性：一项前瞻性队列研究。
Front Aging Neurosci. 2025 Apr 9;17:1556608. doi: 10.3389/fnagi.2025.1556608. eCollection 2025.
5
Impact of Olive Oil Components on the Expression of Genes Related to Type 2 Diabetes Mellitus.橄榄油成分对2型糖尿病相关基因表达的影响。
Nutrients. 2025 Feb 3;17(3):570. doi: 10.3390/nu17030570.
6
Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging.来自英国生物银行的多维度证据表明饮食和常量营养素摄入对衰老的影响。
Commun Med (Lond). 2025 Feb 4;5(1):36. doi: 10.1038/s43856-025-00754-5.
7
Targeting the Gut Microbiota for Prevention and Management of Type 2 Diabetes.靶向肠道微生物群预防和管理 2 型糖尿病。
Nutrients. 2024 Nov 19;16(22):3951. doi: 10.3390/nu16223951.
8
Beyond Blood Sugar: Low Awareness of Kidney Disease among Type 2 Diabetes Mellitus Patients in Dalmatia-Insights from the First Open Public Call.超越血糖：达尔马提亚 2 型糖尿病患者对肾脏疾病认识不足——首次公开公共呼吁的见解。
Medicina (Kaunas). 2024 Oct 8;60(10):1643. doi: 10.3390/medicina60101643.
9
Age-specific association between meal-skipping patterns and the risk of hyperglycemia in Korean adults: a national cross-sectional study using the KNHANES data.韩国成年人中不同年龄段的饮食不规律模式与高血糖风险的相关性：基于 KNHANES 数据的全国性横断面研究。
BMC Public Health. 2024 Jun 25;24(1):1697. doi: 10.1186/s12889-024-18762-w.
10
Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects.地中海饮食在慢性病的靶向预防和个性化治疗中的应用：证据、潜在机制及前景
EPMA J. 2024 Apr 16;15(2):207-220. doi: 10.1007/s13167-024-00360-w. eCollection 2024 Jun.
本文引用的文献
1
Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90.撤稿与重新发表：地中海饮食对心血管疾病的一级预防。《新英格兰医学杂志》2013年；368卷：1279 - 1290页。
N Engl J Med. 2018 Jun 21;378(25):2441-2442. doi: 10.1056/NEJMc1806491. Epub 2018 Jun 13.
2
Comparative effect of two Mediterranean diets versus a low-fat diet on glycaemic control in individuals with type 2 diabetes.两种地中海饮食与低脂饮食对2型糖尿病患者血糖控制的比较效果
Eur J Clin Nutr. 2014 Jul;68(7):767-72. doi: 10.1038/ejcn.2014.1. Epub 2014 Feb 12.
3
Nutrition therapy recommendations for the management of adults with diabetes.成人糖尿病管理的营养治疗建议。
Diabetes Care. 2013 Nov;36(11):3821-42. doi: 10.2337/dc13-2042. Epub 2013 Oct 9.
4
The association between dietary patterns and type 2 diabetes: a systematic review and meta-analysis of cohort studies.饮食模式与2型糖尿病之间的关联：队列研究的系统评价与荟萃分析
J Hum Nutr Diet. 2014 Jun;27(3):251-60. doi: 10.1111/jhn.12139. Epub 2013 Sep 16.
5
Relation of the Mediterranean diet with the incidence of gestational diabetes.地中海饮食与妊娠糖尿病发生率的关系。
Eur J Clin Nutr. 2014 Jan;68(1):8-13. doi: 10.1038/ejcn.2013.177. Epub 2013 Oct 2.
6
Mediterranean diet and glycaemic load in relation to incidence of type 2 diabetes: results from the Greek cohort of the population-based European Prospective Investigation into Cancer and Nutrition (EPIC).地中海饮食和血糖负荷与 2 型糖尿病发病风险的关系：基于人群的欧洲癌症与营养前瞻性调查（EPIC）希腊队列研究结果。
Diabetologia. 2013 Nov;56(11):2405-13. doi: 10.1007/s00125-013-3013-y. Epub 2013 Aug 22.
7
Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review.饮食模式分析与低度炎症生物标志物：系统文献回顾。
Nutr Rev. 2013 Aug;71(8):511-27. doi: 10.1111/nure.12035. Epub 2013 Jun 13.
8
Mediterranean diet adherence in individuals with prediabetes and unknown diabetes: the Di@bet.es Study.在患有糖尿病前期和未知糖尿病的个体中地中海饮食的坚持情况：Di@bet.es 研究。
Ann Nutr Metab. 2013;62(4):339-46. doi: 10.1159/000346553. Epub 2013 Jul 2.
9
Consumption of cereal fiber, mixtures of whole grains and bran, and whole grains and risk reduction in type 2 diabetes, obesity, and cardiovascular disease.食用谷物纤维、全谷物和麦麸混合物以及全谷物可降低 2 型糖尿病、肥胖症和心血管疾病的风险。
Am J Clin Nutr. 2013 Aug;98(2):594-619. doi: 10.3945/ajcn.113.067629. Epub 2013 Jun 26.
10
The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease.地中海饮食可改善非酒精性脂肪肝患者的肝脂肪变性和胰岛素敏感性。
J Hepatol. 2013 Jul;59(1):138-43. doi: 10.1016/j.jhep.2013.02.012. Epub 2013 Feb 26.
Zotero 插件