Bauml Joshua, Langer Corey J, Evans Tracey, Garland Sheila N, Desai Krupali, Mao Jun J
Department of Medicine, Division of Hematology/Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Support Care Cancer. 2014 Sep;22(9):2465-72. doi: 10.1007/s00520-014-2220-5. Epub 2014 Apr 9.
Scant literature exists on the use of complementary and alternative medicine (CAM) among patients with lung cancer. Preliminary data indicates that perceived control is an important factor leading patients to CAM. This study aimed to evaluate the relationship between perceived control and CAM use in patients with lung cancer.
We performed a cross-sectional survey in patients with lung cancer under active treatment and follow-up at the oncology clinic of an academic medical center. Self-reported CAM use was the primary outcome. Multivariate logistic regression was performed to determine the relationship between perceived control and CAM use, controlling for other factors.
Among 296 participants, 54.4 % were female, 83.5 % were Caucasian, 57.6 % were ≤65 years old, 52.4 % were in stage IV, and 86.4 % had non-small cell lung cancer; 50.9 % of patients had used CAM, most commonly vitamins (31.5 %), herbs (19.3 %), relaxation techniques (16 %), and special diets (15.7 %). In multivariate analysis, CAM use was associated with having greater perceived control over the cause of cancer (adjusted odds ratio (AOR) 2.27, 95 % confidence interval (CI) 1.35-3.80), age ≤ 65 (AOR 1.64, 95 % CI 1.01-2.67), higher education (AOR 2.17, 95 % CI 1.29-3.64), and never having smoked tobacco (AOR 2.39, 95 % CI 1.25-4.54). Nearly 60 % of patients who used CAM were receiving active treatment.
Over half of lung cancer patients have used CAM since diagnosis. Greater perceived control over the cause of cancer was associated with CAM use. Given the high prevalence of CAM, it is essential that oncologists caring for patients with lung cancer discuss its use.
关于肺癌患者使用补充替代医学（CAM）的文献较少。初步数据表明，感知到的控制感是促使患者使用CAM的一个重要因素。本研究旨在评估肺癌患者感知到的控制感与CAM使用之间的关系。
我们在一家学术医疗中心肿瘤门诊对正在接受积极治疗和随访的肺癌患者进行了横断面调查。自我报告的CAM使用情况是主要结局。进行多因素逻辑回归以确定感知到的控制感与CAM使用之间的关系，并对其他因素进行控制。
在296名参与者中，54.4%为女性，83.5%为白种人，57.6%年龄≤65岁，52.4%处于IV期，86.4%患有非小细胞肺癌；50.9%的患者使用过CAM，最常见的是维生素（31.5%）、草药（19.3%）、放松技巧（16%）和特殊饮食（15.7%）。在多因素分析中，使用CAM与对癌症病因有更强的感知控制感相关（调整后的优势比[AOR] 2.27，95%置信区间[CI] 1.35 - 3.80）、年龄≤65岁（AOR 1.64，95% CI 1.01 - 2.67）、高等教育程度（AOR 2.17，95% CI 1.29 - 3.64）以及从不吸烟（AOR 2.39，95% CI 1.25 - 4.54）。近60%使用CAM的患者正在接受积极治疗。
超过一半的肺癌患者自确诊以来使用过CAM。对癌症病因有更强的感知控制感与使用CAM相关。鉴于CAM的高使用率，照顾肺癌患者的肿瘤学家讨论其使用情况至关重要。
