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精神分裂症与脑血管疾病。一组病例描述及文献综述。

Schizophrenia and cerebrovascular disease. A description of a series and bibliographic reivew.

作者信息

Berrocal-Izquierdo Nuria, Bernardo Miguel

机构信息

Parc Sanitari Sant Joan de Dèu. Servicio de Neurología. Sant Boi de Llobregat, Barcelona.

Programa de Esquizofrenia Clínic. Hospital Clínic. Universitat de Barcelona. IDIBAPS. CIBERSAM.

出版信息

Actas Esp Psiquiatr. 2014 Mar-Apr;42(2):74-82. Epub 2014 Mar 1.

PMID:24715365
Abstract

INTRODUCTION

The state of health of patients with schizophrenia is a field of growing interest that has probably not received sufficient attention in the past. It is currently held that physical health should form a part of the overall therapeutic strategy in these patients since reference is made to certain treatable conditions that may affect the final prognosis. One example is cardiovascular disease and its associated reduction in life expectancy.

DEVELOPMENT

We carried out a retrospective study in which we described the consultations held between the psychiatric acute care service and the neurology service during a one-year period. We have analyzed the frequency of cerebrovascular complications in our sample and have included a summary of the most relevant published data regarding cerebrovascular disease (CVD) in patients with schizophrenia.

CONCLUSIONS

We have described the high frequency of CVD in both our series of patients with severe mental illness receiving attention as well as in those from the neurology service (25.7%), and in the subgroup presenting psychotic disorders (25%). There are several studies focusing on the possible causes of increased cardiovascular morbidity and mortality, especially in schizophrenia. However, in regards to CVD specifically, little has been found in the literature and that found shows contradictory results. Given the direct relation between cardiovascular disease and CVD, a consistent relation between CVD and schizophrenia is to be expected.

摘要

引言

精神分裂症患者的健康状况是一个日益受到关注的领域,在过去可能未得到足够重视。目前认为,身体健康应成为这些患者整体治疗策略的一部分,因为某些可治疗的状况可能会影响最终预后。一个例子是心血管疾病及其导致的预期寿命缩短。

发展

我们进行了一项回顾性研究,描述了精神科急性护理服务与神经科服务在一年期间进行的会诊情况。我们分析了样本中脑血管并发症的发生率,并纳入了有关精神分裂症患者脑血管疾病(CVD)的最相关已发表数据的总结。

结论

我们描述了在我们接受治疗的重度精神疾病患者系列以及神经科患者中CVD的高发生率(25.7%),以及在患有精神障碍的亚组中(25%)。有几项研究关注心血管发病率和死亡率增加的可能原因,特别是在精神分裂症中。然而,关于CVD本身,文献中发现的内容很少,且所发现的结果相互矛盾。鉴于心血管疾病与CVD之间的直接关系,可以预期CVD与精神分裂症之间存在一致的关系。

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