Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Phys Med Biol. 2014 May 7;59(9):N27-36. doi: 10.1088/0031-9155/59/9/N27. Epub 2014 Apr 15.
A promising, new, in vivo prostate dosimetry system has been developed for clinical radiation therapy. This work outlines the preliminary end-to-end testing of the accuracy and precision of the new OARtrac scintillation dosimetry system. We tested 94 calibrated plastic scintillation detector (PSD) probes before their final integration into endorectal balloon assemblies. These probes had been calibrated at The University of Texas MD Anderson Cancer Center Dosimetry Laboratory. We used a complete clinical OARtrac system including the PSD probes, charge coupled device camera monitoring system, and the manufacturer's integrated software package. The PSD probes were irradiated at 6 MV in a Solid Water® phantom. Irradiations were performed with a 6 MV linear accelerator using anterior-posterior/posterior-anterior matched fields to a maximum dose of 200 cGy in a 100 cm source-axis distance geometry. As a whole, the OARtrac system has good accuracy with a mean error of 0.01% and an error spread of ±5.4% at the 95% confidence interval. These results reflect the PSD probes' accuracy before their final insertion into endorectal balloons. Future work will test the dosimetric effects of mounting the PSD probes within the endorectal balloon assemblies.
一种有前途的新型活体前列腺剂量测定系统已被开发用于临床放射治疗。这项工作概述了新的 OARtrac 闪烁剂量测定系统的准确性和精密度的端到端初步测试。在最终集成到直肠内球囊组件之前,我们对 94 个经过校准的塑料闪烁探测器(PSD)探头进行了测试。这些探头已在德克萨斯大学 MD 安德森癌症中心剂量学实验室进行了校准。我们使用了完整的临床 OARtrac 系统,包括 PSD 探头、电荷耦合器件相机监测系统和制造商的集成软件包。PSD 探头在 Solid Water® 体模中用 6 MV 进行照射。照射是在 6 MV 直线加速器上进行的,采用前后/后前匹配场,在 100 cm 源轴距几何形状下,最大剂量为 200 cGy。总的来说,OARtrac 系统具有良好的准确性,在 95%置信区间内平均误差为 0.01%,误差分布为±5.4%。这些结果反映了 PSD 探头在最终插入直肠内球囊之前的准确性。未来的工作将测试将 PSD 探头安装在直肠内球囊组件内的剂量测定效果。