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豆类植物成分在 2 型糖尿病中的积极作用。

The active role of leguminous plant components in type 2 diabetes.

机构信息

Department of Internal Medicine, Bytom, Silesian Medical University, 41-902 Bytom, Katowice, Poland.

Department of Human Nutrition, Zabrze, Silesian Medical University, 41-808 Zabrze, Katowice, Poland.

出版信息

Evid Based Complement Alternat Med. 2014;2014:293961. doi: 10.1155/2014/293961. Epub 2014 Mar 11.

Abstract

Diabetes appears to be one of the most frequent noncommunicable diseases in the world. A permanent growth in the incidence of diabetes can be observed and according to the International Diabetes Federation (IDF) the year 2030 will mark the increase in the number of diabetics to 439 mln worldwide. Type 2 diabetes accounts for about 90% of all diabetes incidence. Nutrition model modification not only features the basic element in type 2 diabetes treatment but also constitutes the fundamental factor influencing a morbidity rate decrease. Leguminous plants are a key factor in the diabetic diet; plants such as pulses or soybeans are nutritious products valued highly in nutrition. These legumes are high in the content of wholesome protein and contain large amounts of soluble alimentary fiber fractions, polyunsaturated fatty acids, vitamins and minerals, and bioactive substances with antioxidant, anti-inflammatory, and anticancer activity. They are distinguished by the high amount of bioactive compounds that may interfere with the metabolism of glucose. The most significant bioactive compounds displaying antidiabetic activity in leguminous plants are as follows: genistein and daidzein, alpha-amylase inhibitors, and alpha-glucosidase inhibitors. In vitro research using leguminous plant extracts has confirmed their antidiabetic properties. Leguminous plants should be employed in the promotion of healthy lifestyles in terms of functional food.

摘要

糖尿病似乎是世界上最常见的非传染性疾病之一。可以观察到糖尿病的发病率一直在持续增长,根据国际糖尿病联合会(IDF)的数据,到 2030 年,全球糖尿病患者人数将增加到 4.39 亿。2 型糖尿病占所有糖尿病发病率的约 90%。营养模式的改变不仅是 2 型糖尿病治疗的基本要素,也是影响发病率下降的基本因素。豆科植物是糖尿病饮食的关键因素;豆类如豆类或大豆是营养丰富的产品,在营养方面受到高度重视。这些豆类富含完整的蛋白质,含有大量的可溶性膳食纤维、多不饱和脂肪酸、维生素和矿物质以及具有抗氧化、抗炎和抗癌活性的生物活性物质。它们的特点是含有大量可能干扰葡萄糖代谢的生物活性化合物。在豆科植物中具有抗糖尿病活性的最重要的生物活性化合物如下:染料木黄酮和大豆苷元、α-淀粉酶抑制剂和α-葡萄糖苷酶抑制剂。对豆科植物提取物的体外研究证实了它们的抗糖尿病特性。在功能性食品方面,应该将豆科植物用于促进健康的生活方式。

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