Verma Manjesh Kumar, Pandey Ramesh Kumar, Khanna Richa, Agarwal Jyotsna
Department of Pediatric with Preventive Dentistry, King George's Medical University, Lucknow, Uttar Pradesh, India.
J Indian Soc Pedod Prev Dent. 2014 Apr-Jun;32(2):120-4. doi: 10.4103/0970-4388.130786.
The choice of irrigating solution used in root canals of primary teeth is complicated by their complex morphology and paucity of associated literature. Propolis is a natural product that has gained interest in this context due to its antibacterial effectiveness against several endodontic pathogens.
The present study was undertaken to assess the potential of water-soluble 25% propolis extract against microorganisms present in root canals of primary teeth during endodontic procedures.
The child patients in the age group of 4-7 years with radiographic evidence of carious pulp exposure were included in the study. Definitive selection was done after gaining access into the pulp chamber and root canals of the selected teeth. The clinical and radiographic evidence of pathosis was ruled out for inclusion in the study.
The selected teeth were divided into two groups randomly. In Group A 0.9% isotonic saline and in Group B 25% extract water-soluble propolis were used as irrigating solution, respectively. The bacterial samples were collected both pre- and post-irrigation and were transferred for microbial assay. STAISTISTICAL ANALYSIS: Wilcoxon matched signed rank test was used to compare the pre-and post-irrigation bacterial counts. Mann-Whitney test was used to compare the mean change (pre-post) in bacterial colony counts of groups in the study.
Antimicrobial effectiveness of 25% water-soluble extract of propolis in the root canals of primary teeth was confirmed in the present study. The reduction in the mean bacterial colony counts of all the isolated bacteria was noticed higher in Group B than Group A.
The results of the present study have confirmed that the antibacterial effectiveness of water-soluble extract of propolis in the root canals of primary teeth in vivo. Considering the low toxicity concerns and antibacterial effectiveness, water-soluble extract of 25% propolis can be advocated as a root canal irrigant in endodontic treatment of primary teeth.
乳牙根管冲洗液的选择因乳牙复杂的形态和相关文献的匮乏而变得复杂。蜂胶是一种天然产物，因其对多种牙髓病病原体具有抗菌作用，在这一背景下受到关注。
本研究旨在评估水溶性25%蜂胶提取物在乳牙根管治疗过程中对乳牙根管内微生物的作用。
本研究纳入了4 - 7岁有牙髓暴露影像学证据的儿童患者。在进入所选牙齿的髓腔和根管后进行最终筛选。排除有病变的临床和影像学证据后纳入研究。
将所选牙齿随机分为两组。A组使用0.9%等渗盐水，B组使用25%水溶性蜂胶提取物作为冲洗液。在冲洗前后收集细菌样本并进行微生物检测。
采用Wilcoxon配对符号秩检验比较冲洗前后的细菌计数。采用Mann - Whitney检验比较研究组细菌菌落计数的平均变化（冲洗前 - 冲洗后）。
本研究证实了25%水溶性蜂胶提取物在乳牙根管中的抗菌效果。B组所有分离细菌的平均菌落计数减少量高于A组。
本研究结果证实了水溶性蜂胶提取物在乳牙根管内的体内抗菌效果。考虑到低毒性和抗菌效果，25%蜂胶的水溶性提取物可被推荐作为乳牙根管治疗中的根管冲洗剂。
