纳米银溶液、次氯酸钠和生理盐水在乳牙根管冲洗中抗菌效果的评估
Evaluation of Antimicrobial Efficacy of Nanosilver Solution, Sodium Hypochlorite and Normal Saline in Root Canal Irrigation of Primary Teeth.
作者信息
Moradi Farasat, Haghgoo Roza
机构信息
Department of Pediatric, Faculty of Dentistry, Shahed University, Tehran, Iran.
出版信息
Contemp Clin Dent. 2018 Sep;9(Suppl 2):S227-S232. doi: 10.4103/ccd.ccd_95_18.
BACKGROUND
Bacteria are the main etiological factors in the development of dentinal caries and its progression to pulpal and periapical disease. is the bacterial species most frequently recovered from the root-filled teeth.
AIM
This study aimed to evaluate the antimicrobial effectiveness of nanosilver (NS) solution as an endodontic irrigation solution of primary teeth against .
SETTINGS AND DESIGN
Thirty-six canals of primary teeth were selected for this study.
METHODS AND MATERIALS
Thirty-six canals of primary teeth were prepared up to the file #35 and all of the specimens were sterilized. Then, root canals were inoculated with a suspension containing bacteria. The teeth were then randomly divided into three groups. Antimicrobial effectiveness was evaluated immediately after dividing into groups by counting colony-forming units on brain heart infusion broth plates.
STATISTICAL ANALYSIS
Data were analyzed using Kolmogorov-Smirnov, Welch, and Dunnett's T3 tests.
RESULTS
Sodium hypochlorite showed the highest antimicrobial effectiveness against and showed significant differences compared with normal saline and NS solution ( < 0.001).
CONCLUSION
Based on the results of this study, solution of NS particles can be used as an alternative to other root canal irrigating solutions.
背景
细菌是牙本质龋发展及其进展为牙髓和根尖周疾病的主要病因。 是从根管治疗后的牙齿中最常分离出的细菌种类。
目的
本研究旨在评估纳米银（NS）溶液作为乳牙根管冲洗液对 的抗菌效果。
设置与设计
本研究选取了36颗乳牙的根管。
方法与材料
将36颗乳牙的根管预备至35号锉，并对所有标本进行消毒。然后，用含有 细菌的悬浮液接种根管。然后将牙齿随机分为三组。分组后立即通过在脑心浸液平板上计数菌落形成单位来评估抗菌效果。
统计分析
使用Kolmogorov-Smirnov、Welch和Dunnett's T3检验对数据进行分析。
结果
次氯酸钠对 显示出最高的抗菌效果，与生理盐水和NS溶液相比有显著差异（ < 0.001）。
结论
基于本研究结果，NS颗粒溶液可作为其他根管冲洗液的替代品。
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