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撒哈拉以南非洲地区汉坦病毒宿主多样性的扩大及地理分布

Expanded host diversity and geographic distribution of hantaviruses in sub-Saharan Africa.

作者信息

Kang Hae Ji, Stanley William T, Esselstyn Jacob A, Gu Se Hun, Yanagihara Richard

机构信息

Departments of Pediatrics and Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA.

Science and Education, Field Museum of Natural History, Chicago, Illinois, USA.

出版信息

J Virol. 2014 Jul;88(13):7663-7. doi: 10.1128/JVI.00285-14. Epub 2014 Apr 16.

Abstract

The recent discovery of hantaviruses in shrews and bats in West Africa suggests that other genetically distinct hantaviruses exist in East Africa. Genetic and phylogenetic analyses of newfound hantaviruses, detected in archival tissues from the Geata mouse shrew (Myosorex geata) and Kilimanjaro mouse shrew ( Myosorex zinki) captured in Tanzania, expands the host diversity and geographic distribution of hantaviruses and suggests that ancestral shrews and/or bats may have served as the original mammalian hosts of primordial hantaviruses.

摘要

最近在西非的鼩鼱和蝙蝠体内发现了汉坦病毒,这表明东非可能存在其他基因不同的汉坦病毒。对在坦桑尼亚捕获的吉阿塔麝鼩(Myosorex geata)和乞力马扎罗麝鼩(Myosorex zinki)的存档组织中检测到的新发现汉坦病毒进行的基因和系统发育分析,扩大了汉坦病毒的宿主多样性和地理分布,并表明祖先鼩鼱和/或蝙蝠可能是原始汉坦病毒的最初哺乳动物宿主。

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