Laboratoire de Procédés Biologiques, Génie Enzymatique et Microbien (ProBioGEM), IUT A/Polytech'Lille, Université de Lille1-Science et Technologies, Avenue Paul Langevin, 59655, Villeneuve d'Ascq Cedex, France.
Arch Microbiol. 2014 Jul;196(7):453-72. doi: 10.1007/s00203-014-0983-1. Epub 2014 Apr 18.
The biofilm formation on abiotic surfaces in food and medical sectors constitutes a great public health concerns. In fact, biofilms present a persistent source for pathogens, such as Pseudomonas aeruginosa and Staphylococcus aureus, which lead to severe infections such as foodborne and nosocomial infections. Such biofilms are also a source of material deterioration and failure. The environmental conditions, commonly met in food and medical area, seem also to enhance the biofilm formation and their resistance to disinfectant agents. In this regard, this review highlights the effect of environmental conditions on bacterial adhesion and biofilm formation on abiotic surfaces in the context of food and medical environment. It also describes the current and emergent strategies used to study the biofilm formation and its eradication. The mechanisms of biofilm resistance to commercialized disinfectants are also discussed, since this phenomenon remains unclear to date.
生物膜在食品和医疗领域的非生物表面的形成是一个重大的公共卫生关注点。事实上，生物膜是病原菌（如铜绿假单胞菌和金黄色葡萄球菌）的持续来源，这些病原菌会导致严重的感染，如食源性和医院获得性感染。这些生物膜也是材料恶化和失效的根源。食品和医疗领域常见的环境条件似乎也会促进生物膜的形成及其对消毒剂的抵抗力。在这方面，本综述强调了环境条件对食品和医疗环境中非生物表面细菌附着和生物膜形成的影响。它还描述了目前和新兴的用于研究生物膜形成及其清除的策略。还讨论了生物膜对商业化消毒剂的抗性机制，因为这一现象至今仍不清楚。
