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Potential impact of environmental bacteriophages in spreading antibiotic resistance genes.环境噬菌体对抗生素耐药基因传播的潜在影响。
Future Microbiol. 2013 Jun;8(6):739-51. doi: 10.2217/fmb.13.32.
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Nucleic Acids Res. 2011 Jul;39(Web Server issue):W347-52. doi: 10.1093/nar/gkr485. Epub 2011 Jun 14.
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The changing epidemiology of resistance.耐药性不断变化的流行病学。
J Antimicrob Chemother. 2009 Sep;64 Suppl 1:i3-10. doi: 10.1093/jac/dkp256.
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Conjugative IncFI plasmids carrying CTX-M-15 among Escherichia coli ESBL producing isolates at a University hospital in Germany.德国一家大学医院产超广谱β-内酰胺酶的大肠埃希菌分离株中携带CTX-M-15的接合型IncFI质粒
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Resistance plasmid families in Enterobacteriaceae.肠杆菌科中的耐药性质粒家族。
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The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
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GECO--linear visualization for comparative genomics.GECO——用于比较基因组学的线性可视化工具。
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tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence.tRNAscan-SE：用于改进基因组序列中转运RNA基因检测的程序。
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编码CTX-M-15的噬菌体样质粒pECOH89的全基因组序列

Complete Genome Sequence of Phage-Like Plasmid pECOH89, Encoding CTX-M-15.

作者信息

Falgenhauer Linda, Yao Yancheng, Fritzenwanker Moritz, Schmiedel Judith, Imirzalioglu Can, Chakraborty Trinad

机构信息

Institute of Medical Microbiology, Justus-Liebig-University Giessen, Giessen, Germany.

出版信息

Genome Announc. 2014 Apr 24;2(2):e00356-14. doi: 10.1128/genomeA.00356-14.

DOI:10.1128/genomeA.00356-14
PMID:24762941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3999498/
Abstract

A nonconjugative and nontypable plasmid of a clinical Escherichia coli isolate expressing resistance to extended-spectrum cephalosporins (ESCs) was isolated and sequenced. The plasmid pECOH89 contains a CTX-M-15 resistance cassette and comprises 111,741 bp, with strong homology to bacteriophage-like plasmids and to the Salmonella-specific bacteriophage SSU5.

摘要

分离并测序了一株临床大肠杆菌分离株的非接合性和不可分型质粒，该质粒对超广谱头孢菌素（ESCs）具有抗性。质粒pECOH89包含一个CTX-M-15抗性盒，大小为111,741 bp，与噬菌体样质粒和沙门氏菌特异性噬菌体SSU5具有高度同源性。