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恶性心包积液手术后的生存情况。

Survival post surgery for malignant pericardial effusion.

作者信息

Nguyen Olivier, Ouellette Denise

机构信息

Faculty of Surgery, University of Montreal;

Thoracic Surgeon, Maisonneuve-Rosemont Hospital, Affiliated to the University of Montreal, Quebec, Canada.

出版信息

Clin Pract. 2011 May 30;1(2):e38. doi: 10.4081/cp.2011.e38. eCollection 2011 May 16.

Abstract

The study reviews the survival of patients with malignant pericardial effusion treated with a subxiphoid pericardial window. The medical records of 60 consecutive patients diagnosed with a malignant pericardial effusion and treated with a subxiphoid pericardial window between 1994 and 2008 were reviewed. 72% had lung cancer. Overall 30-day mortality was 31%. Survival rates at 3 months, 6 months, 1 year, and 2 years were 45%, 28%, 17%, and 9%, respectively. Overall median survival was 2.6 months. Patients with malignant pericardial effusion, especially those with primary lung cancer have poor survival rates. In advanced malignancy, the subxiphoid pericardial window procedure provides only short-term palliation of symptoms, and has no effect on long-term survival. The use of any surgical procedure in patients with malignant advanced pericardial effusion should be considered along with non-surgical options on a case-by-case basis depending on symptoms, general status, and expected survival.

摘要

本研究回顾了采用剑突下心包开窗术治疗恶性心包积液患者的生存情况。对1994年至2008年间连续60例诊断为恶性心包积液并接受剑突下心包开窗术治疗的患者的病历进行了回顾。其中72%患有肺癌。总体30天死亡率为31%。3个月、6个月、1年和2年的生存率分别为45%、28%、17%和9%。总体中位生存期为2.6个月。恶性心包积液患者,尤其是原发性肺癌患者的生存率较低。在晚期恶性肿瘤中,剑突下心包开窗术仅能短期缓解症状,对长期生存无影响。对于晚期恶性心包积液患者,应根据症状、一般状况和预期生存期,逐例综合考虑采用任何外科手术及非手术治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae18/3981241/5aeae4727b88/cp-2011-2-e38-g001.jpg

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