用于动脉粥样硬化斑块特征分析的血管内超声-光学相干断层扫描集成成像
Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization.
作者信息
Li Xiang, Li Jiawen, Jing Joe, Ma Teng, Liang Shanshan, Zhang Jun, Mohar Dilbahar, Raney Aidan, Mahon Sari, Brenner Matthew, Patel Pranav, Shung K Kirk, Zhou Qifa, Chen Zhongping
机构信息
NIH Ultrasonic Transducer Resource Center and the Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, USA.
Department of Biomedical Engineering, the Edwards Life Sciences Center for Advanced Cardiovascular Technology, and Beckman Laser Institute, University of California, Irvine, CA 92697 USA.
出版信息
IEEE J Sel Top Quantum Electron. 2014 Mar;20(2):7100108. doi: 10.1109/JSTQE.2013.2274724.
For the diagnosis of atherosclerosis, biomedical imaging techniques such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed. The combined use of IVUS and OCT is hypothesized to remarkably increase diagnostic accuracy of vulnerable plaques. We have developed an integrated IVUS-OCT imaging apparatus, which includes the integrated catheter, motor drive unit, and imaging system. The dual-function imaging catheter has the same diameter of current clinical standard. The imaging system is capable for simultaneous IVUS and OCT imaging in real time. and experiments on rabbits with atherosclerosis were conducted to demonstrate the feasibility and superiority of the integrated intravascular imaging modality.
为了诊断动脉粥样硬化，已经开发了诸如血管内超声（IVUS）和光学相干断层扫描（OCT）等生物医学成像技术。据推测，IVUS和OCT的联合使用可显著提高易损斑块的诊断准确性。我们开发了一种集成的IVUS-OCT成像设备，它包括集成导管、电机驱动单元和成像系统。这种具有双重功能的成像导管与当前临床标准导管直径相同。该成像系统能够实时同时进行IVUS和OCT成像。并且对患有动脉粥样硬化的兔子进行了实验，以证明这种集成血管内成像方式的可行性和优越性。
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