Zhou Li-Wei, Wei Yu-Lian, Dai Yu-Cheng
State Key Laboratory of Forest and Soil Ecology, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110164, P. R. China.
Mycology. 2014 Mar;5(1):29-42. doi: 10.1080/21501203.2014.895784. Epub 2014 Mar 25.
White-rot and brown-rot fungi employ different mechanisms to degrade lignocellulose. These fungi are not monophyletic and even alternate in their common lineage. To explore the reason for this, seventy-six ligninolytic peroxidases (LPs), including 14 sequences newly identified from available basidiomycetous whole-genome and EST databases in this study, were utilized for phylogenetic and selective pressure analyses. We demonstrate that LPs were subjected to the mixed process of concerted and birth-and-death evolution. After the duplication events of original LPs, various LP types may originate from mutation events of several key residues driven by positive selection, which may change LP types and even rot types in a small fraction of wood-decaying fungi. Our findings provide preliminary insights into the cause for the alternation of the two fungal rot types within the same lineage.
白腐菌和褐腐菌采用不同的机制来降解木质纤维素。这些真菌并非单系类群，甚至在其共同谱系中交替出现。为探究其原因，本研究利用了76种木质素分解过氧化物酶（LP）进行系统发育和选择压力分析，其中包括从现有担子菌全基因组和EST数据库中新鉴定出的14个序列。我们证明，LP经历了协同进化和生死进化的混合过程。在原始LP发生复制事件后，各种LP类型可能源自正选择驱动的几个关键残基的突变事件，这可能会改变一小部分木材腐朽真菌中的LP类型甚至腐朽类型。我们的研究结果为同一谱系中两种真菌腐朽类型交替出现的原因提供了初步见解。
