Li Shuang, Chen Ai-Jun, Fang Sheng, Li Hui
Departments of Dermatology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Dermatol Ther. 2014 Sep-Oct;27(5):304-6. doi: 10.1111/dth.12133. Epub 2014 Apr 28.
Necrobiotic xanthogranuloma (NXG) is a rare granulomatous condition that is often associated with a paraproteinemia and in some cases multiple myeloma. We report a case of isolated NXG that responded very well to total glucosides of paeony treatment. Characteristic clinical and histological features of NXG are presented, as well as a discussion regarding management and the use of glucosides of paeony. Treatment with total glucosides of paeony is an effective, safe treatment, which avoids the side effects associated with systemic corticosteroid or cytotoxic agent therapy.
