Faramarzi Mahbobeh, Kheirkhah Farzan, Shokri-Shirvani Javad, Mosavi Shokofeh, Zarini Soroush
Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran.
Department of Psychiatry, Babol University of Medical Sciences, Ayatollah Rouhani Hospital, Babol, Iran.
Caspian J Intern Med. 2014 Spring;5(2):71-6.
The role of psychological factors in peptic ulcer disease (PUD) and functional dyspepsia (FD) has not been clearly determined. In this study the role of conflict management styles, psychiatric symptoms, and alexithymia were assessed in patients with PUD and FD and in the healthy individuals.
Ninety subjects [30 PUD (15 women, 15 men), 30 FD (15 women, 15 men), and 30 healthy individuals (15 women, 15 men)] in two endoscopy wards of Babol University of Medical Sciences were evaluated. Three groups were matched with regard to demographic variables. Conflict management styles, psychiatric symptoms, and alexithymia were evaluated by appropriate questionnaires.
The patients with PUD reported less mean scores on psychiatric symptoms than the FD patients (depression 12.6±7.5 vs 28±9.5, anxiety 8.2±5.9 vs 18.7±6. obsessive-compulsive disorder 15.7±7.5 vs 21.8±8.4, interpersonal sensitivity 9.5±7.4 vs 16±7, psychoticism 8.03±4.5 vs 14.3±6.3, somatization 12.5±10.8 vs 20.7±8.1, and the total score of psychiatric symptoms 94.4±49.9 vs 160.1±46.6). The mean scores use of unconstructive conflict management styles in PUD patients were lower than FD (dominating 17.7±3.5 vs 20.2±2.7, avoiding 17.5±3 vs 23.8±4.4). Alexithymia symptoms were higher in FD patients than PUD individuals (difficulty in identifying feelings 23.5±6.3 vs 27.8±3.9, difficulty in describing feeling 16.5±4.4 vs 17.3±3.6). The PUD and FD patients had higher scores regarding these variables than the healthy subjects.
The results show that both PUD and FD patients experienced more psychiatric symptoms, unconstructive conflict management styles, and alexithymia than the healthy subjects. FD patients had worse psychiatric problems than PUD.
心理因素在消化性溃疡病（PUD）和功能性消化不良（FD）中的作用尚未明确确定。在本研究中，对PUD和FD患者以及健康个体的冲突管理方式、精神症状和述情障碍的作用进行了评估。
对巴博尔医科大学两个内镜病房的90名受试者[30名PUD患者（15名女性，15名男性），30名FD患者（15名女性，15名男性）和30名健康个体（15名女性，15名男性）]进行了评估。三组在人口统计学变量方面进行了匹配。通过适当的问卷对冲突管理方式、精神症状和述情障碍进行了评估。
PUD患者的精神症状平均得分低于FD患者（抑郁12.6±7.5对28±9.5，焦虑8.2±5.9对18.7±6，强迫症15.7±7.5对21.8±8.4，人际敏感性9.5±7.4对16±7，精神质8.03±4.5对14.3±6.3，躯体化12.5±10.8对20.7±8.1，精神症状总分94.4±49.9对160.1±46.6）。PUD患者使用非建设性冲突管理方式的平均得分低于FD患者（支配型17.7±3.5对20.2±2.7，回避型17.5±3对23.8±4.4）。FD患者的述情障碍症状高于PUD患者（识别情感困难23.5±6.3对27.8±3.9，描述情感困难16.5±4.4对17.3±3.6）。PUD和FD患者在这些变量上的得分高于健康受试者。
结果表明，PUD和FD患者比健康受试者经历了更多的精神症状、非建设性冲突管理方式和述情障碍。FD患者的精神问题比PUD患者更严重。
