Hindorf Cecilia, Oddstig Jenny, Hedeer Fredrik, Hansson Magnus J, Jögi Jonas, Engblom Henrik
Department of Radiation Physics, Skåne University Hospital, Lund, Sweden,
J Nucl Cardiol. 2014 Aug;21(4):695-702. doi: 10.1007/s12350-014-9897-1. Epub 2014 May 8.
Myocardial perfusion single photon emission computed tomography (MPS) is one of the most widely used diagnostic methods in patients with suspected ischemic heart disease (IHD). Recently, a novel technique based on cadmium-zinc-telluride (CZT) detectors, pinhole collimators, and a stationary gantry was introduced for MPS. The aim of this work was to investigate how patient positioning affects the reconstructed MPS images using this novel technique.
Eighteen patients referred for a clinical MPS due to suspected IHD were included in the study. All patients underwent MPS imaging on a GE Discovery NM 530c CZT camera. After image acquisition with the heart positioned in the center of the quality field of view (QFOV), the patients were re-imaged in different positions 5-20 mm off-center. The heart was still positioned within the limits of the QFOV during the off-center scans. The summed stress score and/or the summed rest score (SSS and/or SRS) for the acquisition performed in the center was compared to the same parameter for the acquisitions performed off-center.
There was a statistically significant increase in SSS and/or SRS when imaging was performed with the heart 5-20 mm outside the center of the QFOV compared to optimal positioning (7.7 ± 1.3 vs 6.6 ± 1.3, P = .006). The SSS and/or SRS increased with ≥2 U in 35% (14/40) of the off-center examinations.
It is important to carefully position the patient's heart within the center of the QFOV when performing MPS with the Discovery NM 530c CZT camera to avoid positioning-related image artifacts that could affect the diagnostic accuracy.
心肌灌注单光子发射计算机断层扫描(MPS)是疑似缺血性心脏病(IHD)患者中使用最广泛的诊断方法之一。最近,一种基于碲化镉锌(CZT)探测器、针孔准直器和固定机架的新技术被引入用于MPS。这项工作的目的是研究患者体位如何影响使用这种新技术重建的MPS图像。
本研究纳入了18例因疑似IHD而接受临床MPS检查的患者。所有患者均在GE Discovery NM 530c CZT相机上进行MPS成像。在心脏位于质量视野(QFOV)中心进行图像采集后,患者在偏离中心5-20mm的不同位置重新成像。在偏心扫描过程中,心脏仍位于QFOV范围内。将中心位置采集的总应力评分和/或总静息评分(SSS和/或SRS)与偏心位置采集的相同参数进行比较。
与最佳定位相比,当心脏在QFOV中心以外5-20mm处成像时,SSS和/或SRS有统计学显著增加(7.7±1.3对6.6±1.3,P=0.006)。在35%(14/40)的偏心检查中,SSS和/或SRS增加≥2 U。
使用Discovery NM 530c CZT相机进行MPS检查时,将患者心脏小心地定位在QFOV中心内很重要,以避免可能影响诊断准确性的与定位相关的图像伪影。