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The relative trustworthiness of inferential tests of the indirect effect in statistical mediation analysis: does method really matter?统计中介分析中间接效应推断检验的相对可信度:方法真的重要吗?
Psychol Sci. 2013 Oct;24(10):1918-27. doi: 10.1177/0956797613480187. Epub 2013 Aug 16.
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Does childhood attention-deficit/hyperactivity disorder predict risk-taking and medical illnesses in adulthood?儿童注意缺陷多动障碍是否会预测成年后的冒险行为和医疗疾病?
J Am Acad Child Adolesc Psychiatry. 2013 Feb;52(2):153-162.e4. doi: 10.1016/j.jaac.2012.11.012. Epub 2013 Jan 5.
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Attention-deficit/hyperactivity disorder and adverse health outcomes.注意缺陷多动障碍与不良健康结局。
Clin Psychol Rev. 2013 Mar;33(2):215-28. doi: 10.1016/j.cpr.2012.11.005. Epub 2012 Dec 7.
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Preventive interventions for ADHD: a neurodevelopmental perspective.ADHD 的预防干预:神经发育观点。
Neurotherapeutics. 2012 Jul;9(3):531-41. doi: 10.1007/s13311-012-0123-z.
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Youth risk behavior surveillance - United States, 2011.青少年危险行为监测-美国,2011 年。
MMWR Surveill Summ. 2012 Jun 8;61(4):1-162.
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Annual research review: categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders--implications of recent empirical study.年度研究综述:儿童和青少年精神障碍分类和概念化中的类别与维度——近期实证研究的启示。
J Child Psychol Psychiatry. 2012 May;53(5):469-89. doi: 10.1111/j.1469-7610.2011.02511.x. Epub 2012 Jan 31.
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Prospective association of childhood attention-deficit/hyperactivity disorder (ADHD) and substance use and abuse/dependence: a meta-analytic review.前瞻性关联研究:儿童注意缺陷多动障碍(ADHD)与物质使用和滥用/依赖的关系:一项荟萃分析综述。
Clin Psychol Rev. 2011 Apr;31(3):328-41. doi: 10.1016/j.cpr.2011.01.006. Epub 2011 Jan 20.
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A gradient of childhood self-control predicts health, wealth, and public safety.儿童时期自我控制能力的梯度变化可以预测健康、财富和公共安全。
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Psychiatric disorders and sexual risk among adolescents in mental health treatment.精神健康治疗中的青少年精神障碍和性风险。
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Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity: a meta-analysis.遗传和环境因素对注意缺陷多动障碍的注意不集中和多动症状维度的影响:一项荟萃分析。
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青少年中的注意力缺陷多动障碍与危险性行为:品行问题和物质使用作为风险的中介因素

ADHD and risky sexual behavior in adolescents: conduct problems and substance use as mediators of risk.

作者信息

Sarver Dustin E, McCart Michael R, Sheidow Ashli J, Letourneau Elizabeth J

机构信息

Center to Promote Effective Youth Development (Youth-Nex), University of Virginia, Charlottesville, VA, USA.

出版信息

J Child Psychol Psychiatry. 2014 Dec;55(12):1345-53. doi: 10.1111/jcpp.12249. Epub 2014 May 12.

DOI:10.1111/jcpp.12249
PMID:24813803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4479401/
Abstract

BACKGROUND

Recent studies have linked attention-deficit/hyperactivity disorder (ADHD) to elevated rates of risky sexual behavior (RSB) in adult samples. The current study tested whether ADHD symptoms were associated with RSB among adolescents, and examined comorbid conduct problems and problematic substance use as joint mediators of this association.

METHODS

ADHD symptoms, conduct problems (oppositional defiant disorder/conduct disorder symptoms), problematic alcohol use (alcohol use disorder symptoms, alcohol use frequency), problematic marijuana use (marijuana use disorder symptoms, marijuana use frequency), and RSB were assessed among an ethnically diverse cross-sectional sample of adolescents (N = 115; mean age = 14.9 years) involved in the juvenile justice system.

RESULTS

Bootstrapped mediation models revealed an initial association between ADHD symptoms and RSB that was accounted for fully by the influence of problematic alcohol and marijuana use, but not conduct problems. A follow-up multiple groups mediation analysis demonstrated that the relationship between ADHD symptoms and RSB emerged only among youth with clinically elevated conduct problems, and that problematic marijuana use fully accounted for this relationship. Hyperactive/impulsive, but not inattentive, symptoms were related to RSB, although the pattern of indirect effects was consistent with the multiple groups analysis.

CONCLUSIONS

The association between ADHD and adolescent RSB is restricted to youth with elevated comorbid conduct problems and reflects the contributions of comorbid marijuana use problems, and to a lesser extent alcohol use problems. Early identification and treatment of these comorbid conditions may be important for the prevention of negative sexual health outcomes among youth with ADHD.

摘要

背景

近期研究已将注意力缺陷多动障碍(ADHD)与成年样本中危险性性行为(RSB)发生率升高联系起来。本研究测试了ADHD症状是否与青少年中的RSB相关,并检查了共病的品行问题和问题性物质使用作为这种关联的联合中介因素。

方法

在参与少年司法系统的一个种族多样化的青少年横断面样本(N = 115;平均年龄 = 14.9岁)中,评估了ADHD症状、品行问题(对立违抗障碍/品行障碍症状)、问题性酒精使用(酒精使用障碍症状、酒精使用频率)、问题性大麻使用(大麻使用障碍症状、大麻使用频率)和RSB。

结果

自抽样中介模型显示ADHD症状与RSB之间最初存在关联,该关联完全由问题性酒精和大麻使用的影响所解释,但不由品行问题所解释。后续的多组中介分析表明,ADHD症状与RSB之间的关系仅在临床品行问题升高的青少年中出现,且问题性大麻使用完全解释了这种关系。多动/冲动症状而非注意力不集中症状与RSB相关,尽管间接效应模式与多组分析一致。

结论

ADHD与青少年RSB之间的关联仅限于共病品行问题升高的青少年,反映了共病大麻使用问题的影响,在较小程度上也反映了酒精使用问题的影响。早期识别和治疗这些共病情况对于预防ADHD青少年的负面性健康结果可能很重要。