Norén Selinus E, Molero Y, Lichtenstein P, Anckarsäter H, Lundström S, Bottai M, Hellner Gumpert C
Department of Clinical Neuroscience, Centre for Psychiatry Research & Education, Karolinska Institutet & Stockholm County Council, Stockholm, Sweden.
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Acta Psychiatr Scand. 2016 Dec;134(6):533-545. doi: 10.1111/acps.12655. Epub 2016 Oct 7.
To examine the association between different levels of childhood attention deficit hyperactivity disorder (ADHD) symptoms and sex differences in psychosocial outcomes during adolescence.
Swedish children (n = 4635) were screened for neuropsychiatric symptoms at age 9 or 12. ADHD symptoms were divided into three levels: screen-negative, screen-intermediate, and screen-positive. At follow-up (age 15), parents and teenagers filled out questionnaires regarding (i) hyperactivity/inattention, (ii) peer problems, (iii) school problems, (iv) internalizing problems, (v) antisocial behaviour, (vi) alcohol misuse, and (vii) drug misuse. All outcomes were controlled for symptoms of diagnostic categories other than ADHD.
Increasing levels of ADHD symptoms in childhood were associated with higher proportions of adolescents who displayed negative psychosocial outcomes. More girls than boys reported internalizing problems (all levels) and risky drug use (screen-intermediate and screen-positive only). More boys reported antisocial behaviour at the screen-negative and screen-intermediate levels, but at the screen-positive level, similar proportions of girls and boys displayed antisocial behaviour.
The findings support the view that ADHD symptoms, as well as their negative outcomes, are dimensionally distributed in the population and that adolescent girls and boys display different risk profiles. The findings confirm that ADHD symptoms are associated with higher risk of drug misuse in girls.
探讨儿童期不同程度的注意力缺陷多动障碍(ADHD)症状与青春期心理社会结局的性别差异之间的关联。
对4635名瑞典儿童在9岁或12岁时进行神经精神症状筛查。ADHD症状分为三个水平:筛查阴性、筛查中等和筛查阳性。在随访(15岁)时,父母和青少年填写了关于以下方面的问卷:(i)多动/注意力不集中,(ii)同伴问题,(iii)学校问题,(iv)内化问题,(v)反社会行为,(vi)酒精滥用,以及(vii)药物滥用。所有结局均对ADHD以外诊断类别的症状进行了控制。
儿童期ADHD症状水平的升高与出现负面心理社会结局的青少年比例较高相关。报告内化问题(所有水平)和危险药物使用(仅筛查中等和筛查阳性水平)的女孩多于男孩。在筛查阴性和筛查中等水平,报告反社会行为的男孩更多,但在筛查阳性水平,表现出反社会行为的女孩和男孩比例相似。
研究结果支持以下观点,即ADHD症状及其负面结局在人群中呈维度分布,且青春期女孩和男孩表现出不同的风险特征。研究结果证实,ADHD症状与女孩药物滥用的较高风险相关。