Children's Hospital Informatics Program at Harvard-MIT Health Sciences and Technology, Boston, Massachusetts, USA Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA Harvard Catalyst, Harvard Medical School, Boston, Massachusetts, USA Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA Harvard Catalyst, Harvard Medical School, Boston, Massachusetts, USA.
J Am Med Inform Assoc. 2014 Jul-Aug;21(4):615-20. doi: 10.1136/amiajnl-2014-002727. Epub 2014 May 12.
We describe the architecture of the Patient Centered Outcomes Research Institute (PCORI) funded Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS, http://www.SCILHS.org) clinical data research network, which leverages the $48 billion dollar federal investment in health information technology (IT) to enable a queryable semantic data model across 10 health systems covering more than 8 million patients, plugging universally into the point of care, generating evidence and discovery, and thereby enabling clinician and patient participation in research during the patient encounter. Central to the success of SCILHS is development of innovative 'apps' to improve PCOR research methods and capacitate point of care functions such as consent, enrollment, randomization, and outreach for patient-reported outcomes. SCILHS adapts and extends an existing national research network formed on an advanced IT infrastructure built with open source, free, modular components.
我们描述了患者中心的成果研究所（PCORI）资助的可扩展协作学习医疗系统基础设施（SCILHS，http://www.SCILHS.org）临床数据研究网络的架构，该网络利用了联邦政府在健康信息技术（IT）上的 480 亿美元投资，实现了 10 个健康系统中超过 800 万患者的可查询语义数据模型，普遍适用于护理点，生成证据和发现，从而使临床医生和患者能够在患者就诊期间参与研究。SCILHS 的成功关键在于开发创新的“应用程序”，以改进 PCOR 研究方法，并实现护理点功能，如同意、登记、随机化和患者报告结果的外展。SCILHS 改编并扩展了一个现有的国家研究网络，该网络建立在一个使用开源、免费、模块化组件构建的先进 IT 基础设施上。
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