Chaitchik S, Shenberg C, Nir-El Y, Mantel M
Elias Sourasky Medical Center Tel-Aviv, Israel.
Biol Trace Elem Res. 1988 Jan-Apr;15:205-12. doi: 10.1007/BF02990137.
A preliminary study was carried out in order to compare the selenium concentration in breast cancer patients and healthy subjects (controls) in Israel. Blood serum samples were obtained from 32 breast cancer patients and 36 controls and were analyzed for selenium by the XRF method. A weighted mean of 0.076 +/- 0.014 ppm Se in the blood serum of breast cancer patients, as compared to 0.119 +/- 0.023 ppm Se for controls, was obtained. These results indicate that the concentration of selenium in breast cancer patients is significantly lower than in controls. The relationship between selenium concentration and malignancy stage shows an inverse dependence, i.e., the concentration decreases with stage number.
为比较以色列乳腺癌患者与健康受试者（对照组）的硒浓度，开展了一项初步研究。从32名乳腺癌患者和36名对照者身上采集血清样本，并用X射线荧光光谱法分析其中的硒。乳腺癌患者血清中硒的加权平均值为0.076±0.014 ppm，而对照组为0.119±0.023 ppm。这些结果表明，乳腺癌患者体内的硒浓度显著低于对照组。硒浓度与恶性肿瘤分期之间呈负相关，即浓度随分期数增加而降低。
