Anschutz Health and Wellness Center, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
Obesity (Silver Spring). 2014 Jun;22(6):1415-21. doi: 10.1002/oby.20737.
To compare the efficacy of non-nutritive sweetened beverages (NNS) or water for weight loss during a 12-week behavioral weight loss treatment program.
An equivalence trial design with water or NNS beverages as the main factor in a prospective randomized trial among 303 men and women was employed. All participants participated in a behavioral weight loss treatment program. The results of the weight loss phase (12 weeks) of an ongoing trial (1 year) that is also evaluating the effects of these two treatments on weight loss maintenance were reported.
The two treatments were not equivalent with the NNS beverage treatment group losing significantly more weight compared to the water group (5.95 kg versus 4.09 kg; P < 0.0001) after 12 weeks. Participants in the NNS beverage group reported significantly greater reductions in subjective feelings of hunger than those in the water group during 12 weeks.
These results show that water is not superior to NNS beverages for weight loss during a comprehensive behavioral weight loss program.
比较在为期 12 周的行为减肥治疗计划中，非营养性甜味饮料（NNS）或水对于减肥的效果。
采用等效试验设计，在一项前瞻性随机试验中，以水或 NNS 饮料为主要因素，纳入 303 名男性和女性。所有参与者均参加了行为减肥治疗计划。报告了正在进行的试验（1 年）减肥阶段（12 周）的结果，该试验还评估了这两种治疗方法对减肥维持的影响。
两种治疗方法不等效，与水组相比，NNS 饮料治疗组在 12 周后体重明显减轻（5.95 千克对 4.09 千克；P<0.0001）。在 12 周期间，NNS 饮料组报告的主观饥饿感明显低于水组。
这些结果表明，在综合行为减肥计划中，水并不优于 NNS 饮料来减肥。
