Ferrer Pili, Ballarín Elena, Sabaté Mònica, Laporte Joan-Ramon, Schoonen Marieke, Rottenkolber Marietta, Fortuny Joan, Hasford Joerg, Tatt Iain, Ibáñez Luisa
Fundació Institut Català de Farmacologia, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Int J Public Health. 2014 Oct;59(5):877-87. doi: 10.1007/s00038-014-0564-8. Epub 2014 May 30.
This study aimed at outlining the characteristics of nationwide administrative databases monitoring drug consumption in Europe.
Internet and bibliographic databases (April 2010) were searched and experts in drug utilization (DU) research interviewed to find nationwide administrative medicines consumption databases in Europe, with data for the out- and inpatient healthcare sector. A questionnaire was developed to gather additional information. We collected data providers, websites, accessibility, data sources, healthcare settings, population coverage, medicines-related data, patient and prescriber data, periods covered, and linkage to other databases.
Thirty-one administrative nationwide medicine consumption databases in 25 countries were identified. Questionnaires were responded for 20 databases. Eleven provided wholesalers' sales data, 11 on reimbursed, 5 on prescribed, and 4 on dispensing medicines. Fifteen databases provided inpatient drug consumption data, mainly wholesalers' sales.
Nationwide administrative databases are of value to all stakeholders involved in the conduct and interpretation of post-marketing safety studies, and in the conduct of DU research. The endorsement of the anatomical therapeutic chemical/defined daily dose methodology by these databases contributes to data harmonization. However, there is still a lack of information on inpatient medicines consumption at a patient-level.
本研究旨在概述欧洲监测药物消费的全国性行政数据库的特征。
检索互联网和文献数据库（2010年4月），并采访药物利用（DU）研究领域的专家，以查找欧洲的全国性行政药品消费数据库，包括门诊和住院医疗部门的数据。设计了一份问卷以收集更多信息。我们收集了数据提供者、网站、可访问性、数据源、医疗保健环境、人口覆盖范围、药品相关数据、患者和开处方者数据、涵盖的时间段以及与其他数据库的链接等信息。
在25个国家识别出31个全国性行政药品消费数据库。20个数据库回复了问卷。11个提供批发商销售数据，11个提供报销药品数据，5个提供处方药品数据，4个提供配药数据。15个数据库提供住院药品消费数据，主要是批发商的销售数据。
全国性行政数据库对参与上市后安全性研究的开展和解读以及药物利用研究的所有利益相关者都具有价值。这些数据库对解剖治疗化学/限定日剂量方法的认可有助于数据协调。然而，在患者层面上，关于住院药品消费的信息仍然缺乏。
