Van Dyke C, Jatlow P, Ungerer J, Barash P G, Byck R
Science. 1978 Apr 14;200(4338):211-3. doi: 10.1126/science.24895.
Cocaine (2.0 milligrams per kilogram) given by the oral route is at least as effective as the same dose given intranasally. Cocaine is not detected in the plasma until 30 minutes after oral administration, but peak plasma concentrations are similar after both routes. The subjective "highs" in man are greater after oral than after intranasal administration.
口服给予可卡因（2.0毫克/千克）的效果至少与经鼻给予相同剂量的效果相同。口服给药后30分钟血浆中才检测到可卡因，但两种给药途径后的血浆峰值浓度相似。人体口服给药后的主观“兴奋感”比经鼻给药后的更强。
