Gridneva Zoya, Rea Alethea, Lai Ching Tat, Tie Wan Jun, Kugananthan Sambavi, Murray Kevin, Hartmann Peter E, Geddes Donna T
School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Mathematics and Statistics, Murdoch University, Murdoch, WA 6150, Australia.
Nutrients. 2021 Sep 21;13(9):3294. doi: 10.3390/nu13093294.
This study aimed to investigate relationships between infant abdominal visceral and subcutaneous adiposity and human milk (HM) components and maternal body composition (BC) during first year of lactation. Subcutaneous-abdominal depth (SAD), subcutaneous-abdominal fat area (SFA), visceral depth (VD) and preperitoneal fat area of 20 breastfed infants were assessed at 2, 5, 9 and 12 months using ultrasound. Maternal BC was determined with bioimpedance spectroscopy. HM macronutrients and bioactive components concentrations and infant 24-h milk intake were measured and calculated daily intakes (CDI) determined. Maternal adiposity associated with infant SFA (negatively at 2, 5, 12, positively at 9 months, all overall < 0.05). 24-h milk intake positively associated with infant SAD ( = 0.007) and VD ( = 0.013). CDI of total protein ( = 0.013), total carbohydrates ( = 0.004) and lactose ( = 0.013) positively associated with SFA. Lactoferrin concentration associated with infant VD (negatively at 2, 12, positively at 5, 9 months, overall = 0.003). CDI of HM components and maternal adiposity have differential effects on development of infant visceral and subcutaneous abdominal adiposity. Maintaining healthy maternal BC and continuing breastfeeding to 12 months and beyond may facilitate favourable BC development reducing risk of obesity.
本研究旨在调查哺乳期第一年婴儿腹部内脏和皮下脂肪与母乳（HM）成分及母体身体成分（BC）之间的关系。在2、5、9和12个月时，使用超声评估了20名母乳喂养婴儿的皮下腹部深度（SAD）、皮下腹部脂肪面积（SFA）、内脏深度（VD）和腹膜前脂肪面积。通过生物电阻抗光谱法测定母体身体成分。测量了母乳中的常量营养素和生物活性成分浓度，并计算了婴儿24小时的奶摄入量及确定了每日摄入量（CDI）。母体肥胖与婴儿SFA相关（2、5、12个月时呈负相关，9个月时呈正相关，总体均P<0.05）。24小时奶摄入量与婴儿SAD（P = 0.007）和VD（P = 0.013）呈正相关。总蛋白（P = 0.013）、总碳水化合物（P = 0.004）和乳糖（P = 0.013）的CDI与SFA呈正相关。乳铁蛋白浓度与婴儿VD相关（2、12个月时呈负相关，5、9个月时呈正相关，总体P = 0.003）。母乳成分的CDI和母体肥胖对婴儿内脏和皮下腹部肥胖的发展有不同影响。保持母体健康的身体成分并持续母乳喂养至12个月及以后可能有助于促进有利的身体成分发展，降低肥胖风险。
