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中国大陆首例2型糖尿病患者发生非O1/非O139群霍乱弧菌血症病例。

The first case of bacteraemia due to non-O1/non-O139 Vibrio cholerae in a type 2 diabetes mellitus patient in mainland China.

作者信息

Lu Binghuai, Zhou Haijian, Li Dong, Li Fengjuan, Zhu Fengxia, Cui Yanchao, Huang Lei, Wang Duochun

机构信息

Department of Laboratory Medicine, Civil Aviation General Hospital, Beijing, China.

National Institute for Communicable Disease Control and Prevention, and State Key Laboratory for Infectious Disease Prevention and Control, Chinese Centre for Disease Control and Prevention, 155, Changbai Road, Changping, Beijing 102206, China; Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.

出版信息

Int J Infect Dis. 2014 Aug;25:116-8. doi: 10.1016/j.ijid.2014.04.015. Epub 2014 Jun 4.

Abstract

Bacteraemia due to non-O1/non-O139 Vibrio cholerae is rarely documented in mainland China. We report such a case in a 70-year-old male with type 2 diabetes mellitus. The clinical features, phenotypic analyses, and presence of a panel of known virulence genes in the isolated strain are described. To the best of our knowledge, this is the first reported case of bacteraemia due to this strain in a T2DM patient without other coexisting underlying diseases in mainland China.

摘要

非O1/非O139型霍乱弧菌引起的菌血症在中国大陆鲜有报道。我们报告了一名70岁2型糖尿病男性患者的此类病例。描述了分离菌株的临床特征、表型分析以及一组已知毒力基因的存在情况。据我们所知,这是中国大陆首例报道的由该菌株引起的、无其他并存基础疾病的2型糖尿病患者菌血症病例。

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