Rocha Marco Alexandre, Costa Caroline Sousa, Bagatin Edileia
Escola Paulista de Medicina - Universidade Federal de Sao Paulo (EPM-Unifesp), Brazil.
Inflamm Allergy Drug Targets. 2014;13(3):162-7. doi: 10.2174/1871528113666140606110024.
Acne is a chronic self-limited disease, which affects mostly teenagers, without gender difference. In recent years, the incidence has increased in female adults. The factors involved in this epidemiological observation are still under discussion in the literature. Clinically, acne is characterized by different types of lesions. The disease affects the regions rich in sebaceous glands (face, chest and upper back). The clinical lesions are: open and closed comedones, erythematous papules, pustules, nodules and different types of scars. Taking into consideration the general concept of inflammation (redness, pain, heat and loss of function), acne is traditionally classified as non-inflammatory (open and closed comedones) and inflammatory (other primary lesions). With the knowledge advancement this concept seems to be wrong and therefore acne would be an inflammatory disease even before the onset of their clinical lesions.
痤疮是一种慢性自限性疾病，主要影响青少年，无性别差异。近年来，成年女性的发病率有所上升。文献中仍在讨论这一流行病学观察结果所涉及的因素。临床上，痤疮以不同类型的皮损为特征。该病影响皮脂腺丰富的区域（面部、胸部和上背部）。临床皮损有：开放性和闭合性粉刺、红斑丘疹、脓疱、结节以及不同类型的瘢痕。考虑到炎症的一般概念（发红、疼痛、发热和功能丧失），痤疮传统上分为非炎症性（开放性和闭合性粉刺）和炎症性（其他原发性皮损）。随着知识的进步，这一概念似乎是错误的，因此痤疮甚至在临床皮损出现之前就是一种炎症性疾病。
