Kumar Sandeep, Lather Viney, Pandita Deepti
Department of Pharmaceutics, JCDM College of Pharmacy, Sirsa-125055, Haryana, India.
Department of Pharmaceutical Chemistry, JCDM College of Pharmacy, Sirsa-125055, Haryana, India.
Nanomedicine (Lond). 2015;10(15):2451-71. doi: 10.2217/nnm.15.112. Epub 2015 Jul 31.
Nanotechnology continues to achieve tremendous awards in therapeutics, but the economical and ecofriendly production of nanoparticles (NPs) is still in infancy, simply due to the nanotoxicity, unprecedented health hazards and scale up issues. Green nanotechnology was introduced in the quest to mitigate such risks by utilizing natural resources as biological tool for NP synthesis. The key advantages offered by green approach include lower capital and operating expenses, reduced environmental impacts, superior biocompatibility and higher stability. In this review, we shed light on the biosynthesis of therapeutic NPs along with their numerous biomedical applications. Toxicity aspects of NPs and the impact of green approach on it, is also discussed briefly.
纳米技术在治疗领域不断斩获重大成果，但纳米颗粒（NPs）的经济且环保的生产仍处于起步阶段，这仅仅是因为纳米毒性、前所未有的健康危害以及扩大生产规模的问题。绿色纳米技术应运而生，旨在通过利用自然资源作为纳米颗粒合成的生物工具来降低此类风险。绿色方法所具有的关键优势包括更低的资本和运营成本、减少对环境的影响、卓越的生物相容性以及更高的稳定性。在这篇综述中，我们阐述了治疗性纳米颗粒的生物合成及其众多生物医学应用。同时，还简要讨论了纳米颗粒的毒性问题以及绿色方法对其的影响。
