伊朗德黑兰一家教学医院临床医学实验室不同检测阶段的错误类型及发生率
Types and Frequency of Errors during Different Phases of Testing At a Clinical Medical Laboratory of a Teaching Hospital in Tehran, Iran.
作者信息
Abdollahi Alireza, Saffar Hiva, Saffar Hana
机构信息
Department of Clinical Pathology, Central Laboratory, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
N Am J Med Sci. 2014 May;6(5):224-8. doi: 10.4103/1947-2714.132941.
Abstract
BACKGROUND
According to official data, 60-70% of clinical decisions about hospitalization and discharge are based on laboratory results.
AIMS
The objective of this study is to examine the frequency of errors before, during, and after analysis in a major medical laboratory.
MATERIALS AND METHODS
This descriptive, cross-sectional study was conducted throughout 2012 (January-December 2012). Errors are recorded by the Quality Control Committee in a specially designed record.
RESULTS
A total of 303,866 samples, 2,430,928 tests were received for analysis. The total number of errors was 153,148 (6.3%) (116,392 for inpatients and 36,756 for outpatients). Analysis of the results revealed that about 65.09% of the errors occur across preanalytical phase, whereas 23.2% and 11.68% are related to analytical and postanalytical phase, respectively.
CONCLUSION
More than half of the laboratory errors are related to preanalytical phase; therefore, proper training and knowledge of intervening factors are essential for reducing errors and optimizing the quality.
摘要
背景
根据官方数据，60%至70%关于住院和出院的临床决策是基于实验室检查结果。
目的
本研究的目的是调查一家大型医学实验室分析前、分析中和分析后的错误发生率。
材料与方法
这项描述性横断面研究于2012年全年（2012年1月至12月）开展。质量控制委员会用专门设计的记录表格记录错误情况。
结果
共收到303,866个样本，进行了2,430,928次检测。错误总数为153,148次（6.3%）（住院患者116,392次，门诊患者36,756次）。结果分析显示，约65.09%的错误发生在分析前阶段，而分析阶段和分析后阶段的错误分别占23.2%和11.68%。
结论
超过半数的实验室错误与分析前阶段有关；因此，针对干扰因素进行适当培训并掌握相关知识对于减少错误和优化质量至关重要。
相似文献
1
Types and Frequency of Errors during Different Phases of Testing At a Clinical Medical Laboratory of a Teaching Hospital in Tehran, Iran.伊朗德黑兰一家教学医院临床医学实验室不同检测阶段的错误类型及发生率
N Am J Med Sci. 2014 May;6(5):224-8. doi: 10.4103/1947-2714.132941.
2
Evaluation of preanalytical and postanalytical phases in clinical biochemistry laboratory according to IFCC laboratory errors and patient safety specifications.根据国际临床化学联合会（IFCC）实验室误差和患者安全规范评估临床生物化学实验室的分析前和分析后阶段。
Biochem Med (Zagreb). 2022 Oct 1;32(3):030701. doi: 10.11613/BM.2022.030701. Epub 2022 Aug 5.
3
Prevalence and types of preanalytical error in hematology laboratory of a tertiary care hospital in South India.印度南部一家三级护理医院血液学实验室分析前误差的发生率及类型。
J Lab Physicians. 2018 Apr-Jun;10(2):237-240. doi: 10.4103/JLP.JLP_98_17.
4
Study of the Pre-Analytical Phase of an ISO 15189: 2012-Certified Cytopathology Laboratory: A 5-Year Institutional Experience.一家获得ISO 15189: 2012认证的细胞病理学实验室的分析前阶段研究：一项为期5年的机构经验
Acta Cytol. 2019;63(1):56-62. doi: 10.1159/000494567. Epub 2018 Dec 19.
5
Errors in a stat laboratory: types and frequencies 10 years later.十年后统计实验室的误差：类型与频率
Clin Chem. 2007 Jul;53(7):1338-42. doi: 10.1373/clinchem.2007.088344. Epub 2007 May 24.
6
Errors in laboratory medicine.检验医学中的误差
Clin Chem. 2002 May;48(5):691-8.
7
Preanalytical Errors in a Hematology Laboratory: An Experience from a Tertiary Care Center.血液学实验室的分析前误差：来自三级医疗中心的经验
Diagnostics (Basel). 2023 Feb 6;13(4):591. doi: 10.3390/diagnostics13040591.
8
Recognizing and Reducing Analytical Errors and Sources of Variation in Clinical Pathology Data in Safety Assessment Studies.识别并减少安全性评估研究中临床病理学数据的分析误差和变异来源。
Toxicol Pathol. 2017 Feb;45(2):281-287. doi: 10.1177/0192623316672945. Epub 2016 Nov 15.
9
Errors in the Extra-Analytical Phases of Clinical Chemistry Laboratory Testing.临床化学实验室检测分析前阶段的误差
Indian J Clin Biochem. 2018 Apr;33(2):154-162. doi: 10.1007/s12291-017-0657-2. Epub 2017 May 5.
10
Challenges in Preanalytical Phase of Laboratory Medicine: Rate of Blood Sample Nonconformity in a Tertiary Care Hospital.检验医学分析前阶段的挑战：三级医院血样不合格率
EJIFCC. 2020 Mar 20;31(1):21-27. eCollection 2020 Mar.
引用本文的文献
1
Hospital errors and their consequences among healthcare professionals a: descriptive correlational investigation.医疗保健专业人员中的医院差错及其后果：描述性相关调查
Ann Med Surg (Lond). 2025 May 26;87(7):4026-4033. doi: 10.1097/MS9.0000000000003280. eCollection 2025 Jul.
2
Preanalytical Phase: Evaluation of Specimen Rejection Rates and Reasons from Different Hospital Units during Coronavirus Disease 2019 Pandemic in Saudi Arabia.分析前阶段：沙特阿拉伯2019年冠状病毒病大流行期间不同医院科室标本拒收率及原因评估
Ann Afr Med. 2025 Jul 1;24(3):643-648. doi: 10.4103/aam.aam_132_24. Epub 2025 May 30.
3
Evaluation of pre-analytical errors using six sigma metrics towards quality of laboratory performance in an Indian tertiary care hospital.使用六西格玛指标评估印度一家三级护理医院实验室检测前误差对实验室性能质量的影响。
Bioinformation. 2024 Oct 31;20(10):1418-1423. doi: 10.6026/9732063002001418. eCollection 2024.
4
A comprehensive preanalytical protocol for fresh solid tumor biospecimens.新鲜实体瘤生物标本的全面预分析方案。
Methods. 2024 Sep;229:108-114. doi: 10.1016/j.ymeth.2024.06.005. Epub 2024 Jun 21.
5
Computational pathology: A survey review and the way forward.计算病理学：综述与未来发展方向
J Pathol Inform. 2024 Jan 14;15:100357. doi: 10.1016/j.jpi.2023.100357. eCollection 2024 Dec.
6
Frequency and types of pre-analytical errors in a clinical laboratory of a specialized healthcare hospital.一家专科医院临床实验室分析前误差的频率及类型
Pak J Med Sci. 2024 Jan;40(2ICON Suppl):S70-S74. doi: 10.12669/pjms.40.2(ICON).8963.
7
Assessment of hematology laboratory performance in the total testing process using quality indicators and sigma metrics in the northwest of Ethiopia: A cross-sectional study.使用质量指标和西格玛指标评估埃塞俄比亚西北部全检测过程中的血液学实验室性能：一项横断面研究。
Health Sci Rep. 2024 Jan 22;7(1):e1833. doi: 10.1002/hsr2.1833. eCollection 2024 Jan.
8
Clinical application of a fully automated blood collection robot and its assessment of blood collection quality of anticoagulant specimens.全自动采血机器人的临床应用及其对抗凝标本采血质量的评估。
Front Med (Lausanne). 2023 Sep 5;10:1251963. doi: 10.3389/fmed.2023.1251963. eCollection 2023.
9
Short-term intra-individual variation of urinary biomarkers in dogs with stable chronic kidney disease.稳定期慢性肾病犬尿液生物标志物的个体内短期变异。
J Vet Intern Med. 2023 Jan;37(1):184-190. doi: 10.1111/jvim.16619. Epub 2023 Jan 11.
10
Taking a step back from testing: Preanalytical considerations in molecular infectious disease diagnostics.从检测后退一步：分子传染病诊断中的分析前考虑。
Clin Biochem. 2023 May;115:22-32. doi: 10.1016/j.clinbiochem.2022.12.003. Epub 2022 Dec 8.
本文引用的文献
1
Critical review of laboratory investigations in clinical practice guidelines: proposals for the description of investigation.临床实践指南中实验室检查的批判性评价：检查描述的建议。
Clin Chem Lab Med. 2013 Jun;51(6):1217-26. doi: 10.1515/cclm-2012-0574.
2
Good clinical laboratory practices improved proficiency testing performance at clinical trials centers in Ghana and Burkina Faso.良好的临床实验室规范提高了加纳和布基纳法索临床试验中心的能力验证表现。
PLoS One. 2012;7(6):e39098. doi: 10.1371/journal.pone.0039098. Epub 2012 Jun 29.
3
Non-parametric error distribution analysis from the laboratory calibration of various rainfall intensity gauges.对各种雨量计进行实验室校准的非参数误差分布分析。
Water Sci Technol. 2012;65(10):1745-52. doi: 10.2166/wst.2012.075.
4
An error management system in a veterinary clinical laboratory.兽医临床实验室中的差错管理系统。
J Vet Diagn Invest. 2012 May;24(3):458-68. doi: 10.1177/1040638712441782.
5
Managing the pre- and post-analytical phases of the total testing process.管理总检测过程的分析前和分析后阶段。
Ann Lab Med. 2012 Jan;32(1):5-16. doi: 10.3343/alm.2012.32.1.5. Epub 2011 Dec 20.
6
Effect of pre-analytical errors on quality of laboratory medicine at a neuropsychiatry institute in north India.分析前误差对印度北部一家神经精神病学研究所检验医学质量的影响。
Indian J Clin Biochem. 2011 Jan;26(1):46-9. doi: 10.1007/s12291-010-0082-2. Epub 2010 Nov 16.
7
Role of training activities for the reduction of pre-analytical errors in laboratory samples from primary care.培训活动在减少初级保健实验室样本分析前误差中的作用。
Clin Chim Acta. 2012 Jan 18;413(1-2):166-9. doi: 10.1016/j.cca.2011.09.017. Epub 2011 Sep 22.
8
Pre-analytical workstations: a tool for reducing laboratory errors.分析前工作站：一种减少实验室误差的工具。
Clin Chim Acta. 2009 Jun;404(1):68-74. doi: 10.1016/j.cca.2009.03.024. Epub 2009 Mar 18.
9
Errors in a stat laboratory: types and frequencies 10 years later.十年后统计实验室的误差：类型与频率
Clin Chem. 2007 Jul;53(7):1338-42. doi: 10.1373/clinchem.2007.088344. Epub 2007 May 24.
10
Errors in clinical laboratories or errors in laboratory medicine?临床实验室的错误还是检验医学的错误？
Clin Chem Lab Med. 2006;44(6):750-9. doi: 10.1515/CCLM.2006.123.
Zotero 插件