Reagh Zachariah M, Yassa Michael A
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA Center for Neurobiology of Learning and Memory, University of California, Irvine, California 92697, USA Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California 92697, USA.
Department of Neurobiology and Behavior, University of California, Irvine, California 92697, USA Center for Neurobiology of Learning and Memory, University of California, Irvine, California 92697, USA Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, California 92697, USA Department of Psychological and Brain Sciences, The Johns Hopkins University, Baltimore, Maryland 21218-2686, USA.
Learn Mem. 2014 Jun 16;21(7):342-6. doi: 10.1101/lm.034546.114. Print 2014 Jul.
Most theories of memory assume that representations are strengthened with repetition. We recently proposed Competitive Trace Theory, building on the hippocampus' powerful capacity to orthogonalize inputs into distinct outputs. We hypothesized that repetition elicits a similar but nonidentical memory trace, and that contextual details of traces may compete for representation over time. We designed a task in which objects were incidentally encoded either one or three times. Supporting our theory, repetition improved target recognition, but impaired rejection of similar lures. This suggests that, in contrast to past beliefs, repetition may reduce the fidelity of memory representations.
大多数记忆理论都认为，表征会随着重复而得到强化。我们最近提出了竞争痕迹理论，该理论基于海马体将输入正交化为不同输出的强大能力。我们假设，重复会引发相似但并非完全相同的记忆痕迹，并且随着时间的推移，痕迹的上下文细节可能会竞争表征。我们设计了一项任务，在该任务中，物体被偶然编码一次或三次。支持我们的理论的是，重复提高了目标识别能力，但损害了对相似诱饵的排除能力。这表明，与过去的看法相反，重复可能会降低记忆表征的保真度。
