Maude Richard J, Kingston Hugh W F, Joshi Sonia, Mohanty Sanjib, Mishra Saroj K, White Nicholas J, Dondorp Arjen M
Am J Trop Med Hyg. 2014 Sep;91(3):493-495. doi: 10.4269/ajtmh.14-0116. Epub 2014 Jun 16.
Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved on recovery. Additional study of these features and their potential role in elucidating the pathogenesis of cerebral malaria is warranted.
疟疾性视网膜病变有助于对重症疟疾成年患者的中枢神经系统血管病理学进行详细研究。本文描述了一名患有脑型疟疾的成年人，其视网膜显著变白，伴有相应的视网膜微血管阻塞、血管扩张、血管迂曲增加以及血视网膜屏障渗漏，同时视力下降，所有这些症状在康复后均得到缓解。有必要对这些特征及其在阐明脑型疟疾发病机制中的潜在作用进行进一步研究。
