Mirmiran Parvin, Bahadoran Zahra, Azizi Fereidoun
Parvin Mirmiran, Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran 19395-4763, Iran.
World J Diabetes. 2014 Jun 15;5(3):267-81. doi: 10.4239/wjd.v5.i3.267.
Type 2 diabetes is a complicated metabolic disorder with both short- and long-term undesirable complications. In recent years, there has been growing evidence that functional foods and their bioactive compounds, due to their biological properties, may be used as complementary treatment for type 2 diabetes mellitus. In this review, we have highlighted various functional foods as missing part of medical nutrition therapy in diabetic patients. Several in vitro, animal models and some human studies, have demonstrated that functional foods and nutraceuticals may improve postprandial hyperglycemia and adipose tissue metabolism modulate carbohydrate and lipid metabolism. Functional foods may also improve dyslipidemia and insulin resistance, and attenuate oxidative stress and inflammatory processes and subsequently could prevent the development of long-term diabetes complications including cardiovascular disease, neuropathy, nephropathy and retinopathy. In conclusion available data indicate that a functional foods-based diet may be a novel and comprehensive dietary approach for management of type 2 diabetes.
2型糖尿病是一种复杂的代谢紊乱疾病，伴有短期和长期的不良并发症。近年来，越来越多的证据表明，功能性食品及其生物活性成分因其生物学特性，可作为2型糖尿病的辅助治疗手段。在本综述中，我们强调了各种功能性食品是糖尿病患者医学营养治疗中缺失的部分。多项体外、动物模型以及一些人体研究表明，功能性食品和营养保健品可改善餐后高血糖和脂肪组织代谢，调节碳水化合物和脂质代谢。功能性食品还可改善血脂异常和胰岛素抵抗，减轻氧化应激和炎症过程，进而预防包括心血管疾病、神经病变、肾病和视网膜病变在内的长期糖尿病并发症。总之，现有数据表明，基于功能性食品的饮食可能是一种新颖且全面的2型糖尿病管理饮食方法。
