Na Kyung-Sun, Park Yong-Gyu, Han Kyungdo, Mok Jee Won, Joo Choun-Ki
Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea; Catholic Institutes of Visual Science, The Catholic University of Korea, Seoul, Korea; Department of Health Promotion Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Biostatistics, The Catholic University of Korea, Seoul, Korea.
PLoS One. 2014 Jun 17;9(6):e96461. doi: 10.1371/journal.pone.0096461. eCollection 2014.
To investigate the potential risk factors associated with nuclear, cortical, posterior subcapsular, and anterior polar cataracts (APC) in the Korean population.
This was a population-based, cross-sectional study of 7992 adults (over 40 years of age) from the data of the fourth annual Korea National Health and Nutrition Examination Survey, performed from 2007 to 2009. The presence of lens opacity was examined by slit-lamp biomicroscopy and evaluated according to LOCS II standard photographs. The subtype of cataract present, including nuclear, cortical, posterior subcapsular, and anterior polar cataracts, was noted. Multivariable adjusted logistic regression analysis was conducted to examine the odds ratio (OR) and 95% confidence interval (CI) for association of each specific type of cataract with age, sex, health examination, and medical history.
The prevalence of nuclear, cortical, and posterior subcapsular cataract increased gradually with increasing age. However, the prevalence of APC peaked in the 50- to 59-year-old subjects. All types of cataract except for APCs were more prevalent in women. Oral steroid use was associated with a lower risk of APC.
These findings showed the unique characteristics of APC in the Korean population.
调查韩国人群中与核性、皮质性、后囊下和前极性白内障（APC）相关的潜在危险因素。
这是一项基于人群的横断面研究，研究对象为2007年至2009年进行的第四次韩国国民健康与营养检查调查数据中的7992名成年人（40岁以上）。通过裂隙灯生物显微镜检查晶状体混浊情况，并根据LOCS II标准照片进行评估。记录存在的白内障亚型，包括核性、皮质性、后囊下和前极性白内障。进行多变量调整逻辑回归分析，以检验每种特定类型白内障与年龄、性别、健康检查和病史之间关联的比值比（OR）和95%置信区间（CI）。
核性、皮质性和后囊下白内障的患病率随年龄增长而逐渐增加。然而，APC的患病率在50至59岁的受试者中达到峰值。除APC外，所有类型的白内障在女性中更为普遍。口服类固醇与APC风险较低相关。
这些发现显示了韩国人群中APC的独特特征。
