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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Department of Clinical Biochemistry, John Radcliffe Hospital, Oxford, U.K.

Clin Sci (Lond). 1989 Feb;76(2):165-70. doi: 10.1042/cs0760165.

The metabolic effects of an intravenous lipid emulsion containing medium-chain triacylglycerols (MCT) and long-chain triacylglycerols (LCT) were studied in 16 critically ill, ventilated patients. The effects were compared in a cross-over study with those of a conventional emulsion containing only LCT. 2. The lipid was well tolerated but the metabolic effects of the MCT/LCT infusion differed from those of the LCT infusion. 3. The major differences were a 60% higher insulin concentration and a significantly greater increase in the plasma concentrations of non-esterified fatty acids during MCT/LCT infusion than during LCT infusion. The mean rise in plasma ketone concentration was also higher during MTC/LCT infusion, although this did not reach statistical significance.

对16例危重症通气患者研究了含中链三酰甘油（MCT）和长链三酰甘油（LCT）的静脉脂质乳剂的代谢效应。在一项交叉研究中，将其效应与仅含LCT的传统乳剂的效应进行了比较。2. 脂质耐受性良好，但MCT/LCT输注的代谢效应与LCT输注的不同。3. 主要差异在于，与LCT输注期间相比，MCT/LCT输注期间胰岛素浓度高60%，非酯化脂肪酸的血浆浓度显著升高幅度更大。MTC/LCT输注期间血浆酮浓度的平均升高也更高，尽管这未达到统计学显著性。

Department of Clinical Biochemistry, John Radcliffe Hospital, Oxford, U.K.

Clin Sci (Lond). 1989 Feb;76(2):165-70. doi: 10.1042/cs0760165.

The metabolic effects of an intravenous lipid emulsion containing medium-chain triacylglycerols (MCT) and long-chain triacylglycerols (LCT) were studied in 16 critically ill, ventilated patients. The effects were compared in a cross-over study with those of a conventional emulsion containing only LCT. 2. The lipid was well tolerated but the metabolic effects of the MCT/LCT infusion differed from those of the LCT infusion. 3. The major differences were a 60% higher insulin concentration and a significantly greater increase in the plasma concentrations of non-esterified fatty acids during MCT/LCT infusion than during LCT infusion. The mean rise in plasma ketone concentration was also higher during MTC/LCT infusion, although this did not reach statistical significance.

对16例危重症通气患者研究了含中链三酰甘油（MCT）和长链三酰甘油（LCT）的静脉脂质乳剂的代谢效应。在一项交叉研究中，将其效应与仅含LCT的传统乳剂的效应进行了比较。2. 脂质耐受性良好，但MCT/LCT输注的代谢效应与LCT输注的不同。3. 主要差异在于，与LCT输注期间相比，MCT/LCT输注期间胰岛素浓度高60%，非酯化脂肪酸的血浆浓度显著升高幅度更大。MTC/LCT输注期间血浆酮浓度的平均升高也更高，尽管这未达到统计学显著性。