巴基斯坦人群缺血性心脏病患者的 ABO 血型频率。
ABO blood group frequency in Ischemic heart disease patients in Pakistani population.
机构信息
Dr. Saima Sharif, Assistant Professor, Department of Zoology, Lahore College for Women University, Lahore, Pakistan.
Naureen Anwar, MS student, Department of Zoology, Lahore College for Women University, Lahore, Pakistan.
出版信息
Pak J Med Sci. 2014 May;30(3):593-5. doi: 10.12669/pjms.303.4502.
OBJECTIVES
To determine if there is any significant association between ABO blood groups and ischemic heart disease (IHD).
METHODS
The study was performed at Punjab Institute of Cardiology (PIC), Lahore. Study duration was from January 2012 to September 2012. This study included 200 IHD patients and 230 control individuals. Self design questionnaire was used to collect information regarding risk factors. Standard agglutination test was performed to determine the blood groups. Data was analyzed on SPSS 16.
RESULTS
The prevalence of blood groups in IHD group was 34% in blood group A, 29% in blood group B, 14% in blood group AB and 23% in blood group O. In control group the distribution of B, A, AB and O blood groups were 34.4%, 20.9%, 12.6%, 32.2% respectively. Rh+ve factor was prevalent in 90.5% among IHD group and 92.6% in control subjects. The prevalence of IHD was more in males (63.5%) as compared to females (36.5%). Mean age was 56.4±0.86 (yrs) and BMI was 26.4±0.33 (kg/m(2)). The prevalence of hypertension was 58.5%, diabetes was 53%, family history of cardiac disease was 45%, 35.5% of patients were doing exercise regularly, 58.5% used ghee, and 58% were smokers. C onclusion: Subjects with blood group A had significantly (p< 0.05) higher risk of developing IHD as compare to other blood groups.
目的
确定 ABO 血型与缺血性心脏病（IHD）之间是否存在显著关联。
方法
该研究在拉合尔旁遮普心脏病研究所（PIC）进行。研究时间为 2012 年 1 月至 2012 年 9 月。本研究纳入了 200 例 IHD 患者和 230 名对照个体。使用自行设计的问卷收集有关危险因素的信息。使用标准凝集试验确定血型。在 SPSS 16 上分析数据。
结果
IHD 组的血型分布为 A 型血占 34%，B 型血占 29%，AB 型血占 14%，O 型血占 23%。在对照组中，B、A、AB 和 O 型血的分布分别为 34.4%、20.9%、12.6%和 32.2%。Rh+因子在 IHD 组中占 90.5%，在对照组中占 92.6%。男性（63.5%）比女性（36.5%）更易患 IHD。平均年龄为 56.4±0.86（岁），BMI 为 26.4±0.33（kg/m²）。高血压患病率为 58.5%，糖尿病患病率为 53%，心脏病家族史为 45%，35.5%的患者定期运动，58.5%使用酥油，58%吸烟。结论：与其他血型相比，A 型血的个体发生 IHD 的风险显著增加（p<0.05）。
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