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上颌骨中央巨细胞肉芽肿的一种不寻常表现。

An unusual presentation of a maxillary central giant cell granuloma.

作者信息

Tsichlaki A, George K S, Manisali M

机构信息

St George's Healthcare NHS Trust, London, UK.

出版信息

J Surg Case Rep. 2012 Aug 1;2012(8):7. doi: 10.1093/jscr/2012.8.7.

DOI:10.1093/jscr/2012.8.7
PMID:24960765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3649584/
Abstract

Central Giant Cell Granulomas (CGCG) of the jaw are uncommon benign lesions which usually occur in the mandible in young adults. Here we present a case report of a 45-year-old woman who presented with a 5-month history of right nasal obstruction secondary to a large maxillary CGCG. The age, symptoms at presentation, location and radiographic features were not pathognomonic for this lesion. This case helps to demonstrate the wide variation in the clinical, radiological and histopathological features of CGCC and provides an update in current treatment concepts.

摘要

颌骨中央巨细胞肉芽肿(CGCG)是一种罕见的良性病变,通常发生于年轻成年人的下颌骨。本文报告一例45岁女性,因巨大上颌骨CGCG继发右鼻阻塞5个月前来就诊。该病变的年龄、就诊时症状、部位及影像学特征均无特异性。该病例有助于展示CGCC在临床、放射学及组织病理学特征方面的广泛差异,并提供当前治疗理念的最新情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bcf/3649584/3a84bc0b2b84/jscr-2012-8-7fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bcf/3649584/3a84bc0b2b84/jscr-2012-8-7fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bcf/3649584/3a84bc0b2b84/jscr-2012-8-7fig1.jpg

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本文引用的文献

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Glucocorticoid and calcitonin receptor expression in central giant cell lesions: implications for therapy.糖皮质激素和降钙素受体在中枢性巨细胞病变中的表达:对治疗的影响。
Int J Oral Maxillofac Surg. 2012 Aug;41(8):994-1000. doi: 10.1016/j.ijom.2012.01.017. Epub 2012 Feb 23.
2
Regression of central giant cell granuloma by a combination of imatinib and interferon: a case report.伊马替尼与干扰素联合治疗使中央巨细胞肉芽肿消退:一例报告
Br J Oral Maxillofac Surg. 2009 Jan;47(1):59-61. doi: 10.1016/j.bjoms.2008.05.013. Epub 2008 Jul 24.
3
Central giant cell granuloma of the jaw: a review of the literature with emphasis on therapy options.
颌骨中央巨细胞肉芽肿:文献综述,重点关注治疗选择
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Nov;104(5):603-15. doi: 10.1016/j.tripleo.2007.04.003. Epub 2007 Aug 20.
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Central giant cell granuloma of the jaws: a clinical, radiologic, and histopathologic study of 26 cases.颌骨中央巨细胞肉芽肿:26例临床、放射学及组织病理学研究
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):346-54. doi: 10.1016/j.tripleo.2005.02.060.
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Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla.上颌骨中央巨细胞肉芽肿手术治疗的长期临床和影像学结果
Int J Oral Maxillofac Surg. 2006 Jan;35(1):60-6. doi: 10.1016/j.ijom.2005.03.005.
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7
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