Kaiser Kathryn A, Brown Andrew W, Bohan Brown Michelle M, Shikany James M, Mattes Richard D, Allison David B
From the Office of Energetics, School of Public Health (KAK, AWB, and DBA), the Nutrition Obesity Research Center (KAK, AWB, MMBB, JMS, and DBA), the Department of Nutrition, School of Health Professions (MMBB), and the Division of Preventive Medicine, School of Medicine (JMS), University of Alabama at Birmingham, Birmingham, AL, and the Department of Nutrition Science, Purdue University, West Lafayette, IN (RDM).
Am J Clin Nutr. 2014 Aug;100(2):567-76. doi: 10.3945/ajcn.114.090548. Epub 2014 Jun 25.
A common dietary recommendation for weight loss, especially in lay public outlets, is to eat more fruit and vegetables (F/Vs). Without a compensatory reduction in total energy intake, significant weight loss would be unlikely.
We aimed to synthesize the best available evidence on the effectiveness of the general recommendation to eat more F/Vs for weight loss or the prevention of weight gain.
We searched multiple databases for human randomized controlled trials that evaluated the effect of increased F/V intake on body weight. Inclusion criteria were as follows: ≥15 subjects/ treatment arm, ≥8-wk intervention, a stated primary or secondary outcome of body weight, the stated goal of the intervention was weight or fat loss or the prevention of weight or fat gain, and food intake provided or prescribed was of a variety of F/Vs that remained minimally processed.
Two studies met all criteria; 5 other studies met all criteria but one. The primary analysis indicated an effect size of weight change (outcome of interest) from baseline [standardized mean difference (SMD) for studies that met all criteria] of -0.16 (95% CI: -0.78, 0.46) (P = 0.60). The SMD for 7 studies that met all or most criteria was 0.04 (95% CI: -0.10, 0.17) (P = 0.62).
Studies to date do not support the proposition that recommendations to increase F/V intake or the home delivery or provision of F/Vs will cause weight loss. On the basis of the current evidence, recommending increased F/V consumption to treat or prevent obesity without explicitly combining this approach with efforts to reduce intake of other energy sources is unwarranted. This systematic review and meta-analysis was registered at http://www.crd.york.ac.uk/PROSPERO/ as CRD42013004688.
对于减肥,尤其是在大众媒体中,一个常见的饮食建议是多吃水果和蔬菜(F/V)。如果不相应减少总能量摄入,不太可能实现显著的体重减轻。
我们旨在综合现有最佳证据,以评估增加F/V摄入量以减肥或预防体重增加这一普遍建议的有效性。
我们检索了多个数据库,查找评估增加F/V摄入量对体重影响的人体随机对照试验。纳入标准如下:每个治疗组≥15名受试者、干预时间≥8周、明确提及体重作为主要或次要结局、干预目标为减轻体重或脂肪或预防体重或脂肪增加,以及提供或规定的食物摄入量为各种最少加工的F/V。
两项研究符合所有标准;另有五项研究除一项标准外符合所有标准。初步分析表明,符合所有标准的研究中,从基线开始体重变化(感兴趣的结局)的效应量[标准化均数差(SMD)]为-0.16(95%CI:-0.78,0.46)(P = 0.60)。符合所有或大多数标准的七项研究的SMD为0.04(95%CI:-0.10,0.17)(P = 0.62)。
迄今为止的研究不支持增加F/V摄入量或提供F/V会导致体重减轻这一观点。根据现有证据,在未明确将此方法与减少其他能量来源摄入的努力相结合的情况下,推荐增加F/V摄入量来治疗或预防肥胖是没有依据的。这项系统评价和荟萃分析已在http://www.crd.york.ac.uk/PROSPERO/注册,注册号为CRD42013004688。