Department of Health and Nutrition, Faculty of Health Sciences, Hiroshima Shudo University, Hiroshima, Japan.
Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Int J Obes (Lond). 2024 Oct;48(10):1465-1471. doi: 10.1038/s41366-024-01575-7. Epub 2024 Jul 9.
Higher vegetable intake is being promoted as an initiative to prevent lifestyle-related diseases. Carotenoids are yellow or red pigment components and are widely present in vegetables. Since ingested carotenoids accumulate in the skin, skin carotenoid levels are a quantitative indicator of vegetable intake. Recently, noninvasive optical sensors for assessing skin carotenoid levels were developed. We here examined the association between skin carotenoid scores measured using optical sensors and the presence of metabolic syndrome.
A total of 1618 individuals (604 men and 1014 women) aged ≥ 40 years (mean age 63.1 years) participated in the study. Skin carotenoid scores were determined using a noninvasive optical sensor based on multiple spatially resolved reflectance spectroscopy. Metabolic syndrome was defined based on the Joint Scientific Statement criteria developed by six international scientific societies. Multivariable-adjusted logistic regression models were used.
The prevalence of metabolic syndrome was 31.3% (n = 506). A remarkably strong association was found between higher skin carotenoid scores and lower prevalence of metabolic syndrome after adjusting for confounders. The multivariable-adjusted odds ratio for the presence of metabolic syndrome in individuals with the highest quartile of skin carotenoid scores was 0.39 (95% confidence interval, 0.28-0.55) compared to those with the lowest quartile.
Our findings suggest that higher skin carotenoid scores measured by non-invasive optimal sensors are significantly associated with a lower likelihood of having metabolic syndrome in the general Japanese population.
人们提倡增加蔬菜摄入量，以此作为预防生活方式相关疾病的一种手段。类胡萝卜素是黄色或红色的色素成分，广泛存在于蔬菜中。由于摄入的类胡萝卜素会在皮肤中积累，因此皮肤类胡萝卜素水平是蔬菜摄入量的一个定量指标。最近，开发出了用于评估皮肤类胡萝卜素水平的非侵入性光学传感器。我们在此研究了使用光学传感器测量的皮肤类胡萝卜素评分与代谢综合征之间的关系。
共有 1618 名年龄≥40 岁（平均年龄 63.1 岁）的个体（604 名男性和 1014 名女性）参与了这项研究。使用基于多空间分辨反射光谱的非侵入性光学传感器来确定皮肤类胡萝卜素评分。代谢综合征根据六个国际科学协会制定的联合科学声明标准来定义。使用多变量调整的逻辑回归模型。
代谢综合征的患病率为 31.3%（n=506）。在调整混杂因素后，发现较高的皮肤类胡萝卜素评分与较低的代谢综合征患病率之间存在显著关联。与皮肤类胡萝卜素评分最低四分位数的个体相比，皮肤类胡萝卜素评分最高四分位数的个体发生代谢综合征的多变量调整比值比为 0.39（95%置信区间，0.28-0.55）。
我们的研究结果表明，使用非侵入性光学传感器测量的较高皮肤类胡萝卜素评分与日本一般人群中代谢综合征的发生几率较低显著相关。
